21-Hydroxy Hydrocortisone

Name: 21-Hydroxy Hydrocortisone
Brand: Vaqora Chemicals
SKU: VQ-026072

About 21-Hydroxy Hydrocortisone

Vaqora Chemicals supplies 21-Hydroxy Hydrocortisone, a metabolite or degradation product of Hydrocortisone registered under CAS number 68473-77-8. Formula C21H30O6, molecular weight 378.5 g/mol. Alternative names: 17-Dehydro-21-Hydroxy Hydrocortisone and 17,21-Dihydroxy-corticosterone.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Hydrocortisone, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 21-Hydroxy Hydrocortisone in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Hydrocortisone

View every impurity, metabolite and intermediate we list for Hydrocortisone.

Hydrocortisone impurities

Specifications & identifiers

Chemical identifiers
Product name	21-Hydroxy Hydrocortisone
Catalogue No.	VQ-026072
CAS Number	68473-77-8
IUPAC name	(8S,9S,10R,11S,13S,14S,17R)-17-(2,2-dihydroxyacetyl)-11,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Molecular formula	C₂₁H₃₀O₆
Molecular weight	378.5 g/mol
Exact mass	378.2042
Grade	Reference Standard
HSN code	38229090
InChIKey	AIPUDODNHSFRNT-HRUPCHJUSA-N
SMILES	C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)C(O)O)O)C)O
PubChem CID	68135943

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	4 / 6
TPSA	115 Å²

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P280, P318, P319, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 21-Hydroxy Hydrocortisone?

The CAS Registry Number of 21-Hydroxy Hydrocortisone is 68473-77-8. It is also known as 17-Dehydro-21-Hydroxy Hydrocortisone, 17-Dehydro-21-hydroxy Hydrocortisone (Tautomer Form), 17,21-Dihydroxy-corticosterone.

What is the molecular formula and molecular weight of 21-Hydroxy Hydrocortisone?

21-Hydroxy Hydrocortisone has the molecular formula C21H30O6 and a molecular weight of 378.5 g/mol. Its IUPAC name is (8S,9S,10R,11S,13S,14S,17R)-17-(2,2-dihydroxyacetyl)-11,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one.

What is 21-Hydroxy Hydrocortisone used for?

21-Hydroxy Hydrocortisone is supplied as a characterised reference material related to Hydrocortisone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 21-Hydroxy Hydrocortisone can I order?

We supply 21-Hydroxy Hydrocortisone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 21-Hydroxy Hydrocortisone?

Yes. Every lot of 21-Hydroxy Hydrocortisone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 21-Hydroxy Hydrocortisone be shipped internationally?

Yes. 21-Hydroxy Hydrocortisone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.