2,2`-[5-[(2,5-Dioxotetrahydro-1H-1-pyrrolyl)m… 1301724-97-9

Name: 2,2`-[5-[(2,5-Dioxotetrahydro-1H-1-pyrrolyl)methyl]-1,3-phenylene]di(2-methylpropionitrile)
Brand: Vaqora Chemicals
SKU: VQ-047403

About 2,2`-[5-[(2,5-Dioxotetrahydro-1H-1-pyrrolyl)methyl]-1,3-phenylene]di(2-methylpropionitrile)

Vaqora Chemicals supplies 2,2`-[5-[(2,5-Dioxotetrahydro-1H-1-pyrrolyl)methyl]-1,3-phenylene]di(2-methylpropionitrile), an impurity of Anastrozole registered under CAS number 1301724-97-9. Formula C19H21N3O2, molecular weight 323.4 g/mol. Its systematic (IUPAC) name is 2-[3-(2-cyanopropan-2-yl)-5-[(2,5-dioxopyrrolidin-1-yl)methyl]phenyl]-2-methylpropanenitrile.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Anastrozole impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 2,2`-[5-[(2,5-Dioxotetrahydro-1H-1-pyrrolyl)methyl]-1,3-phenylene]di(2-methylpropionitrile) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Anastrozole

View every impurity, metabolite and intermediate we list for Anastrozole.

Anastrozole impurities

Specifications & identifiers

Chemical identifiers
Product name	2,2`-[5-[(2,5-Dioxotetrahydro-1H-1-pyrrolyl)methyl]-1,3-phenylene]di(2-methylpropionitrile)
Catalogue No.	VQ-047403
CAS Number	1301724-97-9
IUPAC name	2-[3-(2-cyanopropan-2-yl)-5-[(2,5-dioxopyrrolidin-1-yl)methyl]phenyl]-2-methylpropanenitrile
Molecular formula	C₁₉H₂₁N₃O₂
Molecular weight	323.4 g/mol
Exact mass	323.1634
Grade	Reference Standard
HSN code	38229090
InChIKey	DFJDGSMNTWRXQT-UHFFFAOYSA-N
SMILES	CC(C)(C#N)C1=CC(=CC(=C1)CN2C(=O)CCC2=O)C(C)(C)C#N
PubChem CID	169437419

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	0 / 4
TPSA	85 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,2`-[5-[(2,5-Dioxotetrahydro-1H-1-pyrrolyl)methyl]-1,3-phenylene]di(2-methylpropionitrile)?

The CAS Registry Number of 2,2`-[5-[(2,5-Dioxotetrahydro-1H-1-pyrrolyl)methyl]-1,3-phenylene]di(2-methylpropionitrile) is 1301724-97-9. It is also known as 5-[(2,5-Dioxo-1-pyrrolidinyl)methyl]-anastrozole, 2,2'-(5-((2,5-dioxopyrrolidin-1-yl)methyl)-1,3-phenylene)bis(2-methylpropanenitrile).

What is the molecular formula and molecular weight of 2,2`-[5-[(2,5-Dioxotetrahydro-1H-1-pyrrolyl)methyl]-1,3-phenylene]di(2-methylpropionitrile)?

2,2`-[5-[(2,5-Dioxotetrahydro-1H-1-pyrrolyl)methyl]-1,3-phenylene]di(2-methylpropionitrile) has the molecular formula C19H21N3O2 and a molecular weight of 323.4 g/mol. Its IUPAC name is 2-[3-(2-cyanopropan-2-yl)-5-[(2,5-dioxopyrrolidin-1-yl)methyl]phenyl]-2-methylpropanenitrile.

What is 2,2`-[5-[(2,5-Dioxotetrahydro-1H-1-pyrrolyl)methyl]-1,3-phenylene]di(2-methylpropionitrile) used for?

2,2`-[5-[(2,5-Dioxotetrahydro-1H-1-pyrrolyl)methyl]-1,3-phenylene]di(2-methylpropionitrile) is supplied as a characterised reference material related to Anastrozole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,2`-[5-[(2,5-Dioxotetrahydro-1H-1-pyrrolyl)methyl]-1,3-phenylene]di(2-methylpropionitrile) can I order?

We supply 2,2`-[5-[(2,5-Dioxotetrahydro-1H-1-pyrrolyl)methyl]-1,3-phenylene]di(2-methylpropionitrile) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,2`-[5-[(2,5-Dioxotetrahydro-1H-1-pyrrolyl)methyl]-1,3-phenylene]di(2-methylpropionitrile)?

Yes. Every lot of 2,2`-[5-[(2,5-Dioxotetrahydro-1H-1-pyrrolyl)methyl]-1,3-phenylene]di(2-methylpropionitrile) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,2`-[5-[(2,5-Dioxotetrahydro-1H-1-pyrrolyl)methyl]-1,3-phenylene]di(2-methylpropionitrile) be shipped internationally?

Yes. We export 2,2`-[5-[(2,5-Dioxotetrahydro-1H-1-pyrrolyl)methyl]-1,3-phenylene]di(2-methylpropionitrile) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.