2,2-Dimethylthiopropionamide

Name: 2,2-Dimethylthiopropionamide
Brand: Vaqora Chemicals
SKU: VQ-047916

About 2,2-Dimethylthiopropionamide

Listed under CAS 630-22-8, 2,2-Dimethylthiopropionamide is a process intermediate or related compound of Dabrafenib available from Vaqora Chemicals. Its molecular formula is C5H11NS and its molecular weight is 117.22 g/mol. Systematically, it is named 2,2-dimethylpropanethioamide. It is also known as 2,2,2-Trimethylthioacetamide or thiopivalamide.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Process chemists and analysts use it when developing synthetic routes to Dabrafenib, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2,2-Dimethylthiopropionamide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Dabrafenib

View every impurity, metabolite and intermediate we list for Dabrafenib.

Dabrafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	2,2-Dimethylthiopropionamide
Catalogue No.	VQ-047916
CAS Number	630-22-8
IUPAC name	2,2-dimethylpropanethioamide
Molecular formula	C₅H₁₁NS
Molecular weight	117.22 g/mol
Exact mass	117.0612
InChIKey	FJZJUSOFGBXHCV-UHFFFAOYSA-N
SMILES	CC(C)(C)C(=S)N
PubChem CID	3031130

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	1 / 1
TPSA	58.1 Å²
Synonyms	2,2,2-Trimethylthioacetamide, thiopivalamide, Propanethioamide, 2,2-dimethyl-, 2,2,2-Dimethylthiopropionamide, 2-Methyl-2-methylthiopropionamide, Propionamide, 2-methyl-2-methylthio-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,2-Dimethylthiopropionamide?

The CAS Registry Number of 2,2-Dimethylthiopropionamide is 630-22-8. It is also known as 2,2,2-Trimethylthioacetamide, thiopivalamide, Propanethioamide, 2,2-dimethyl-.

What is the molecular formula and molecular weight of 2,2-Dimethylthiopropionamide?

2,2-Dimethylthiopropionamide has the molecular formula C5H11NS and a molecular weight of 117.22 g/mol. Its IUPAC name is 2,2-dimethylpropanethioamide.

What is 2,2-Dimethylthiopropionamide used for?

2,2-Dimethylthiopropionamide is supplied as a characterised reference material related to Dabrafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,2-Dimethylthiopropionamide can I order?

We supply 2,2-Dimethylthiopropionamide, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,2-Dimethylthiopropionamide?

Yes. Every lot of 2,2-Dimethylthiopropionamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,2-Dimethylthiopropionamide be shipped internationally?

Yes. 2,2-Dimethylthiopropionamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.