2,3-Diketo-L-gulonic acid

Name: 2,3-Diketo-L-gulonic acid
Brand: Vaqora Chemicals
SKU: VQ-026376

About 2,3-Diketo-L-gulonic acid

2,3-Diketo-L-gulonic acid (CAS 3445-22-5) is an impurity of Ascorbic acid offered by Vaqora Chemicals. With the molecular formula C6H8O7, it has a molar mass of 192.12 g/mol. Systematically, it is named (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoic acid. Common synonyms include (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate and diketo-gulonic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Ascorbic acid impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2,3-Diketo-L-gulonic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ascorbic acid

View every impurity, metabolite and intermediate we list for Ascorbic acid.

Ascorbic acid impurities

Specifications & identifiers

Chemical identifiers
Product name	2,3-Diketo-L-gulonic acid
Catalogue No.	VQ-026376
CAS Number	3445-22-5
IUPAC name	(4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoic acid
Molecular formula	C₆H₈O₇
Molecular weight	192.12 g/mol
Exact mass	192.027
Grade	Reference Standard
HSN code	38229090
InChIKey	GJQWCDSAOUMKSE-STHAYSLISA-N
SMILES	C([C@@H]([C@H](C(=O)C(=O)C(=O)O)O)O)O
PubChem CID	440390

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.8
H-bond donors / acceptors	4 / 7
TPSA	132 Å²
Synonyms	(4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate, diketo-gulonic acid, L-threo-2,3-hexodiulosonic acid, 2,3-dioxo-4R,5S,6-trihydroxy-hexanoic acid, diketogulonate, 2,3-Dioxo-D-gulonate, (4R,5S)-4,5,6-Trihydroxy-2,3-Dioxo-hexanoic acid, L-threo-2,3-Hexodiulosonic acid (7CI,8CI,9CI)

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,3-Diketo-L-gulonic acid?

The CAS Registry Number of 2,3-Diketo-L-gulonic acid is 3445-22-5. It is also known as (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate, diketo-gulonic acid, L-threo-2,3-hexodiulosonic acid.

What is the molecular formula and molecular weight of 2,3-Diketo-L-gulonic acid?

2,3-Diketo-L-gulonic acid has the molecular formula C6H8O7 and a molecular weight of 192.12 g/mol. Its IUPAC name is (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoic acid.

What is 2,3-Diketo-L-gulonic acid used for?

2,3-Diketo-L-gulonic acid is supplied as a characterised reference material related to Ascorbic acid. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,3-Diketo-L-gulonic acid can I order?

We supply 2,3-Diketo-L-gulonic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,3-Diketo-L-gulonic acid?

Yes. Every lot of 2,3-Diketo-L-gulonic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,3-Diketo-L-gulonic acid be shipped internationally?

Yes. We export 2,3-Diketo-L-gulonic acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.