2,4-Bis(Trifluoromethyl)Benzonitrile

Name: 2,4-Bis(Trifluoromethyl)Benzonitrile
Brand: Vaqora Chemicals
SKU: VQ-050079

About 2,4-Bis(Trifluoromethyl)Benzonitrile

2,4-Bis(Trifluoromethyl)Benzonitrile (CAS 177952-38-4) is a process intermediate or related compound of Bicalutamide offered by Vaqora Chemicals. Formula C9H3F6N, molecular weight 239.12 g/mol. Common synonyms include Benzonitrile, 2,4-bis(trifluoromethyl)- and 2,4-di(trifluoromethyl)benzonitrile.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Bicalutamide, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2,4-Bis(Trifluoromethyl)Benzonitrile in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Bicalutamide

View every impurity, metabolite and intermediate we list for Bicalutamide.

Bicalutamide impurities

Specifications & identifiers

Chemical identifiers
Product name	2,4-Bis(Trifluoromethyl)Benzonitrile
Catalogue No.	VQ-050079
CAS Number	177952-38-4
IUPAC name	2,4-bis(trifluoromethyl)benzonitrile
Molecular formula	C₉H₃F₆N
Molecular weight	239.12 g/mol
Exact mass	239.017
HSN code	2933
InChIKey	RQKXUWGXSNMDDS-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1C(F)(F)F)C(F)(F)F)C#N
PubChem CID	2736117

Physical properties
Physical form	Solid
LogP (XLogP3)	3.4
H-bond donors / acceptors	0 / 7
TPSA	23.8 Å²

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,4-Bis(Trifluoromethyl)Benzonitrile?

The CAS Registry Number of 2,4-Bis(Trifluoromethyl)Benzonitrile is 177952-38-4. It is also known as Benzonitrile, 2,4-bis(trifluoromethyl)-, 2,4-di(trifluoromethyl)benzonitrile, 2,4-bis(trifluoromethyl)benzenecarbonitrile.

What is the molecular formula and molecular weight of 2,4-Bis(Trifluoromethyl)Benzonitrile?

2,4-Bis(Trifluoromethyl)Benzonitrile has the molecular formula C9H3F6N and a molecular weight of 239.12 g/mol. Its IUPAC name is 2,4-bis(trifluoromethyl)benzonitrile.

What is 2,4-Bis(Trifluoromethyl)Benzonitrile used for?

2,4-Bis(Trifluoromethyl)Benzonitrile is supplied as a characterised reference material related to Bicalutamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,4-Bis(Trifluoromethyl)Benzonitrile can I order?

We supply 2,4-Bis(Trifluoromethyl)Benzonitrile, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,4-Bis(Trifluoromethyl)Benzonitrile?

Yes. Every lot of 2,4-Bis(Trifluoromethyl)Benzonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,4-Bis(Trifluoromethyl)Benzonitrile be shipped internationally?

Yes. 2,4-Bis(Trifluoromethyl)Benzonitrile is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.