(2,4-Difluorophenyl)(piperidin-4-yl)methanone… 106266-04-0

Name: (2,4-Difluorophenyl)(piperidin-4-yl)methanone hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-012739

About (2,4-Difluorophenyl)(piperidin-4-yl)methanone hydrochloride

Vaqora Chemicals supplies (2,4-Difluorophenyl)(piperidin-4-yl)methanone hydrochloride, a process intermediate or related compound of Paliperidone registered under CAS number 106266-04-0. Formula C12H14ClF2NO, molecular weight 261.69 g/mol. Common synonyms include 4-(2,4-difluorobenzoyl)piperidine hcl and 4-(2,4-Difluorobenzoyl)piperidine, HCl.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Paliperidone, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (2,4-Difluorophenyl)(piperidin-4-yl)methanone hydrochloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Paliperidone

View every impurity, metabolite and intermediate we list for Paliperidone.

Paliperidone impurities

Specifications & identifiers

Chemical identifiers
Product name	(2,4-Difluorophenyl)(piperidin-4-yl)methanone hydrochloride
Catalogue No.	VQ-012739
CAS Number	106266-04-0
Other CAS	84162-86-7
IUPAC name	(2,4-difluorophenyl)-piperidin-4-ylmethanone;hydrochloride
Molecular formula	C₁₂H₁₄ClF₂NO
Molecular weight	261.69 g/mol
Exact mass	261.0732
Grade	Reference Standard
HSN code	2933
InChIKey	QPJONRGTWKXJLG-UHFFFAOYSA-N
SMILES	C1CNCCC1C(=O)C2=C(C=C(C=C2)F)F.Cl
PubChem CID	18759874

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 4
TPSA	29.1 Å²
Synonyms	4-(2,4-Difluorobenzoyl)piperidine hydrochloride, (2,4-Difluorophenyl)(piperidin-4-yl)methanone hydrochloride, Methanone, (2,4-difluorophenyl)-4-piperidinyl-, hydrochloride (1:1), 4-(2,4-difluorobenzoyl)piperidine hcl, 4-(2,4-difluorobenzoyl)-piperidine hydrochloride, (2,4-difluoro-phenyl)-piperidin-4-yl-methanone hydrochloride, Methanone, (2,4-difluorophenyl)-4-piperidinyl-, hydrochloride, 4-(2,4-Difluorobenzoyl)piperidinehydrochloride, 4-(2,4-Difluorobenzoyl)piperidine, HCl, 4-(2,4-difluoro-benzoyl)-piperidine-hydrochloride, 2,4-difluorophenyl(4-piperidinyl)methanone hydrochloride, (2,4-difluorophenyl)(4-piperidinyl)methanone hydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (2,4-Difluorophenyl)(piperidin-4-yl)methanone hydrochloride?

The CAS Registry Number of (2,4-Difluorophenyl)(piperidin-4-yl)methanone hydrochloride is 106266-04-0. It is also known as 4-(2,4-Difluorobenzoyl)piperidine hydrochloride, (2,4-Difluorophenyl)(piperidin-4-yl)methanone hydrochloride, Methanone, (2,4-difluorophenyl)-4-piperidinyl-, hydrochloride (1:1).

What is the molecular formula and molecular weight of (2,4-Difluorophenyl)(piperidin-4-yl)methanone hydrochloride?

(2,4-Difluorophenyl)(piperidin-4-yl)methanone hydrochloride has the molecular formula C12H14ClF2NO and a molecular weight of 261.69 g/mol.

What is (2,4-Difluorophenyl)(piperidin-4-yl)methanone hydrochloride used for?

(2,4-Difluorophenyl)(piperidin-4-yl)methanone hydrochloride is supplied as a characterised reference material related to Paliperidone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (2,4-Difluorophenyl)(piperidin-4-yl)methanone hydrochloride can I order?

We supply (2,4-Difluorophenyl)(piperidin-4-yl)methanone hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (2,4-Difluorophenyl)(piperidin-4-yl)methanone hydrochloride?

Yes. Every lot of (2,4-Difluorophenyl)(piperidin-4-yl)methanone hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (2,4-Difluorophenyl)(piperidin-4-yl)methanone hydrochloride be shipped internationally?

Yes. (2,4-Difluorophenyl)(piperidin-4-yl)methanone hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.