2,4,5-Trifluorobenzyl chloride

Name: 2,4,5-Trifluorobenzyl chloride
Brand: Vaqora Chemicals
SKU: VQ-033875

About 2,4,5-Trifluorobenzyl chloride

2,4,5-Trifluorobenzyl chloride (CAS 243139-71-1) is a process intermediate or related compound of Baloxavir marboxil offered by Vaqora Chemicals. Its molecular formula is C7H4ClF3 and its molecular weight is 180.55 g/mol. Its systematic (IUPAC) name is 1-(chloromethyl)-2,4,5-trifluorobenzene. Alternative names: Benzene, 1-(chloromethyl)-2,4,5-trifluoro- and 1-(chloromethyl)-2,4,5-trifluoro-benzene.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Baloxavir marboxil, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2,4,5-Trifluorobenzyl chloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Baloxavir marboxil

View every impurity, metabolite and intermediate we list for Baloxavir marboxil.

Baloxavir marboxil impurities

Specifications & identifiers

Chemical identifiers
Product name	2,4,5-Trifluorobenzyl chloride
Catalogue No.	VQ-033875
CAS Number	243139-71-1
IUPAC name	1-(chloromethyl)-2,4,5-trifluorobenzene
Molecular formula	C₇H₄ClF₃
Molecular weight	180.55 g/mol
Exact mass	179.9954
InChIKey	JMXPOOVDUVHJRO-UHFFFAOYSA-N
SMILES	C1=C(C(=CC(=C1F)F)F)CCl
PubChem CID	2777063

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	0 / 3
TPSA	0 Å²
Synonyms	Benzene, 1-(chloromethyl)-2,4,5-trifluoro-, 1-(chloromethyl)-2,4,5-trifluoro-benzene, 1-Chloromethyl-2,4,5-trifluoro-benzene, alpha-Chloro-2,4,5-trifluorotoluene, 1-(chloromethyl)-2,4,5-trifluorobenzen

Safety & hazard information (GHS)

Corrosive

Signal word: Danger

Hazard statements

H290May be corrosive to metals
H314Causes severe skin burns and eye damage
H318Causes serious eye damage

Precautionary statements: P234, P260, P264, P264 + P265, P280, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P317, P321, P363, P390, P405, P406, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,4,5-Trifluorobenzyl chloride?

The CAS Registry Number of 2,4,5-Trifluorobenzyl chloride is 243139-71-1. It is also known as Benzene, 1-(chloromethyl)-2,4,5-trifluoro-, 1-(chloromethyl)-2,4,5-trifluoro-benzene, 1-Chloromethyl-2,4,5-trifluoro-benzene.

What is the molecular formula and molecular weight of 2,4,5-Trifluorobenzyl chloride?

2,4,5-Trifluorobenzyl chloride has the molecular formula C7H4ClF3 and a molecular weight of 180.55 g/mol. Its IUPAC name is 1-(chloromethyl)-2,4,5-trifluorobenzene.

What is 2,4,5-Trifluorobenzyl chloride used for?

2,4,5-Trifluorobenzyl chloride is supplied as a characterised reference material related to Baloxavir marboxil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,4,5-Trifluorobenzyl chloride can I order?

We supply 2,4,5-Trifluorobenzyl chloride, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,4,5-Trifluorobenzyl chloride?

Yes. Every lot of 2,4,5-Trifluorobenzyl chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,4,5-Trifluorobenzyl chloride be shipped internationally?

Yes. 2,4,5-Trifluorobenzyl chloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.