2,6-Difluorophenol

Name: 2,6-Difluorophenol
Brand: Vaqora Chemicals
SKU: VQ-044503

About 2,6-Difluorophenol

2,6-Difluorophenol is an API impurity reference standard carrying the CAS registry number 28177-48-2. With the molecular formula C6H4F2O, it has a molar mass of 130.09 g/mol. Common synonyms include Phenol, 2,6-difluoro-.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of the parent drug substance to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2,6-Difluorophenol in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Specifications & identifiers

Chemical identifiers
Product name	2,6-Difluorophenol
Catalogue No.	VQ-044503
CAS Number	28177-48-2
IUPAC name	2,6-difluorophenol
Molecular formula	C₆H₄F₂O
Molecular weight	130.09 g/mol
Exact mass	130.023
Grade	Reference Standard
HSN code	38229090
InChIKey	CKKOVFGIBXCEIJ-UHFFFAOYSA-N
SMILES	C1=CC(=C(C(=C1)F)O)F
PubChem CID	94392

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	1 / 3
TPSA	20.2 Å²

Safety & hazard information (GHS)

Flammable

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H228Flammable solid
H302Harmful if swallowed
H312Harmful in contact with skin
H314Causes severe skin burns and eye damage
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P210, P240, P241, P260, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P316, P317, P319, P321, P330, P332 + P317, P337 + P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,6-Difluorophenol?

The CAS Registry Number of 2,6-Difluorophenol is 28177-48-2. It is also known as Phenol, 2,6-difluoro-.

What is the molecular formula and molecular weight of 2,6-Difluorophenol?

2,6-Difluorophenol has the molecular formula C6H4F2O and a molecular weight of 130.09 g/mol. Its IUPAC name is 2,6-difluorophenol.

Which grade and pack sizes of 2,6-Difluorophenol can I order?

We supply 2,6-Difluorophenol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,6-Difluorophenol?

Yes. Every lot of 2,6-Difluorophenol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,6-Difluorophenol be shipped internationally?

Yes. 2,6-Difluorophenol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.