(2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]o… 124751-37-7

Name: (2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide
Brand: Vaqora Chemicals
SKU: VQ-022139

About (2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide

(2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide (CAS 124751-37-7) is a metabolite or degradation product of Cevimeline offered by Vaqora Chemicals. With the molecular formula C10H17NO2S, it has a molar mass of 215.31 g/mol. Systematically, it is named (2S,3S,5S)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane] 3-oxide. Alternative names: Cevimeline sulfoxide, trans- and CEV (R)-S-Oxide.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Cevimeline, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Cevimeline

View every impurity, metabolite and intermediate we list for Cevimeline.

Cevimeline impurities

Specifications & identifiers

Chemical identifiers
Product name	(2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide
Catalogue No.	VQ-022139
CAS Number	124751-37-7
IUPAC name	(2S,3S,5S)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane] 3-oxide
Molecular formula	C₁₀H₁₇NO₂S
Molecular weight	215.31 g/mol
Exact mass	215.098
Grade	Reference Standard
HSN code	38229090
InChIKey	CFUGNFXJXCPICM-BXGCZWRVSA-N
SMILES	C[C@H]1O[C@@]2(CN3CCC2CC3)C[S@@]1=O
PubChem CID	91810607

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.2
H-bond donors / acceptors	0 / 4
TPSA	48.8 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide?

The CAS Registry Number of (2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide is 124751-37-7. It is also known as Cevimeline sulfoxide, trans-, CEV (R)-S-Oxide, trans-cevimeline sulfoxide.

What is the molecular formula and molecular weight of (2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide?

(2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide has the molecular formula C10H17NO2S and a molecular weight of 215.31 g/mol. Its IUPAC name is (2S,3S,5S)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane] 3-oxide.

What is (2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide used for?

(2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide is supplied as a characterised reference material related to Cevimeline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide can I order?

We supply (2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide?

Yes. Every lot of (2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide be shipped internationally?

Yes. We export (2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.