(2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl… 42399-51-9

Name: (2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one
Brand: Vaqora Chemicals
SKU: VQ-036707

About (2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one

(2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one (CAS 42399-51-9) is a metabolite or degradation product of Diltiazem offered by Vaqora Chemicals. The compound has the formula C16H15NO3S, corresponding to a molecular weight of 301.4 g/mol. The IUPAC name is (2R,3R)-3-hydroxy-2-(4-methoxyphenyl)-3,5-dihydro-2H-1,5-benzothiazepin-4-one.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Diltiazem, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer (2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Diltiazem

View every impurity, metabolite and intermediate we list for Diltiazem.

Diltiazem impurities

Specifications & identifiers

Chemical identifiers
Product name	(2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one
Catalogue No.	VQ-036707
CAS Number	42399-51-9
IUPAC name	(2R,3R)-3-hydroxy-2-(4-methoxyphenyl)-3,5-dihydro-2H-1,5-benzothiazepin-4-one
Molecular formula	C₁₆H₁₅NO₃S
Molecular weight	301.4 g/mol
Exact mass	301.0773
Grade	Reference Standard
HSN code	38229090
InChIKey	LHBHZALHFIQJGJ-LSDHHAIUSA-N
SMILES	COC1=CC=C(C=C1)[C@@H]2[C@@H](C(=O)NC3=CC=CC=C3S2)O
PubChem CID	854046

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	2 / 4
TPSA	83.9 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one?

The CAS Registry Number of (2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one is 42399-51-9.

What is the molecular formula and molecular weight of (2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one?

(2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one has the molecular formula C16H15NO3S and a molecular weight of 301.4 g/mol. Its IUPAC name is (2R,3R)-3-hydroxy-2-(4-methoxyphenyl)-3,5-dihydro-2H-1,5-benzothiazepin-4-one.

What is (2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one used for?

(2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one is supplied as a characterised reference material related to Diltiazem. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one can I order?

We supply (2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one?

Yes. Every lot of (2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one be shipped internationally?

Yes. We export (2R,3R)-3-Hydroxy-2-(4-methoxy-3-methylphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.