(2R,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-… 156474-21-4

Name: (2R,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane
Brand: Vaqora Chemicals
SKU: VQ-047456

About (2R,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane

Listed under CAS 156474-21-4, (2R,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane is a process intermediate or related compound of Atazanavir available from Vaqora Chemicals. Formula C15H21NO3, molecular weight 263.33 g/mol. Its systematic (IUPAC) name is tert-butyl N-[(1R)-1-[(2R)-oxiran-2-yl]-2-phenylethyl]carbamate. Alternative names: erythro-N-Boc-D-phenylalanine epoxide and (2R,3R)-1,2-Epoxy-(Boc amino)-4-phenylbutane.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Atazanavir, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (2R,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Atazanavir

View every impurity, metabolite and intermediate we list for Atazanavir.

Atazanavir impurities

Specifications & identifiers

Chemical identifiers
Product name	(2R,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane
Catalogue No.	VQ-047456
CAS Number	156474-21-4
IUPAC name	tert-butyl N-[(1R)-1-[(2R)-oxiran-2-yl]-2-phenylethyl]carbamate
Molecular formula	C₁₅H₂₁NO₃
Molecular weight	263.33 g/mol
Exact mass	263.1521
HSN code	2933
InChIKey	NVPOUMXZERMIJK-OLZOCXBDSA-N
SMILES	CC(C)(C)OC(=O)N[C@H](CC1=CC=CC=C1)[C@@H]2CO2
PubChem CID	11357515

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	1 / 3
TPSA	50.9 Å²
Synonyms	erythro-N-Boc-D-phenylalanine epoxide, tert-Butyl ((R)-1-((R)-oxiran-2-yl)-2-phenylethyl)carbamate, tert-Butyl((R)-1-((R)-oxiran-2-yl)-2-phenylethyl)carbamate, (2R,3R)-1,2-Epoxy-(Boc amino)-4-phenylbutane, (R,R) 1-Oxiranyl-2-phenylethylcarbamic acid tert-butyl ester, rel-tert-Butyl ((R)-1-((R)-oxiran-2-yl)-2-phenylethyl)carbamate, [(1R)-1-{(2R)-oxiran-2-yl}-2-phenyl-ethyl]carbamic acid tert-butylester, 1,1-Dimethylethyl N-[(1R)-1-(2R)-2-oxiranyl-2-phenylethyl]carbamate, 2-Methyl-2-propanyl {(1r)-1-[(2r)-2-oxiranyl]-2-phenylethyl}carbamate, tert-butyl N-[(1R)-1-[(2R)-oxiran-2-yl]-2-phenyl-ethyl]carbamate, Carbamic acid, (1-oxiranyl-2-phenylethyl)-, 1,1-dimethylethyl ester, (R,R)-(+/-)-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P305 + P351 + P338, P330, P337 + P317, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (2R,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane?

The CAS Registry Number of (2R,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane is 156474-21-4. It is also known as erythro-N-Boc-D-phenylalanine epoxide, tert-Butyl ((R)-1-((R)-oxiran-2-yl)-2-phenylethyl)carbamate, tert-Butyl((R)-1-((R)-oxiran-2-yl)-2-phenylethyl)carbamate.

What is the molecular formula and molecular weight of (2R,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane?

(2R,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane has the molecular formula C15H21NO3 and a molecular weight of 263.33 g/mol. Its IUPAC name is tert-butyl N-[(1R)-1-[(2R)-oxiran-2-yl]-2-phenylethyl]carbamate.

What is (2R,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane used for?

(2R,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane is supplied as a characterised reference material related to Atazanavir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (2R,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane can I order?

We supply (2R,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (2R,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane?

Yes. Every lot of (2R,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (2R,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane be shipped internationally?

Yes. (2R,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.