(2R,3R)-4,4-Difluoro-2-(hydroxymethyl)-5-oxot… 122111-07-3

Name: (2R,3R)-4,4-Difluoro-2-(hydroxymethyl)-5-oxotetrahydrofuran-3-yl Benzoate
Brand: Vaqora Chemicals
SKU: VQ-037500

About (2R,3R)-4,4-Difluoro-2-(hydroxymethyl)-5-oxotetrahydrofuran-3-yl Benzoate

Vaqora Chemicals supplies (2R,3R)-4,4-Difluoro-2-(hydroxymethyl)-5-oxotetrahydrofuran-3-yl Benzoate, a metabolite or degradation product of Gemcitabine registered under CAS number 122111-07-3. Formula C12H10F2O5, molecular weight 272.2 g/mol. The IUPAC name is [(2R,3R)-4,4-difluoro-2-(hydroxymethyl)-5-oxooxolan-3-yl] benzoate.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Gemcitabine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer (2R,3R)-4,4-Difluoro-2-(hydroxymethyl)-5-oxotetrahydrofuran-3-yl Benzoate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Gemcitabine

View every impurity, metabolite and intermediate we list for Gemcitabine.

Gemcitabine impurities

Specifications & identifiers

Chemical identifiers
Product name	(2R,3R)-4,4-Difluoro-2-(hydroxymethyl)-5-oxotetrahydrofuran-3-yl Benzoate
Catalogue No.	VQ-037500
CAS Number	122111-07-3
IUPAC name	[(2R,3R)-4,4-difluoro-2-(hydroxymethyl)-5-oxooxolan-3-yl] benzoate
Molecular formula	C₁₂H₁₀F₂O₅
Molecular weight	272.2 g/mol
Exact mass	272.0496
Grade	Reference Standard
HSN code	38229090
InChIKey	BIFWGBBUNCUGII-RKDXNWHRSA-N
SMILES	C1=CC=C(C=C1)C(=O)O[C@@H]2[C@H](OC(=O)C2(F)F)CO
PubChem CID	15673516

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	1 / 7
TPSA	72.8 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (2R,3R)-4,4-Difluoro-2-(hydroxymethyl)-5-oxotetrahydrofuran-3-yl Benzoate?

The CAS Registry Number of (2R,3R)-4,4-Difluoro-2-(hydroxymethyl)-5-oxotetrahydrofuran-3-yl Benzoate is 122111-07-3.

What is the molecular formula and molecular weight of (2R,3R)-4,4-Difluoro-2-(hydroxymethyl)-5-oxotetrahydrofuran-3-yl Benzoate?

(2R,3R)-4,4-Difluoro-2-(hydroxymethyl)-5-oxotetrahydrofuran-3-yl Benzoate has the molecular formula C12H10F2O5 and a molecular weight of 272.2 g/mol. Its IUPAC name is [(2R,3R)-4,4-difluoro-2-(hydroxymethyl)-5-oxooxolan-3-yl] benzoate.

What is (2R,3R)-4,4-Difluoro-2-(hydroxymethyl)-5-oxotetrahydrofuran-3-yl Benzoate used for?

(2R,3R)-4,4-Difluoro-2-(hydroxymethyl)-5-oxotetrahydrofuran-3-yl Benzoate is supplied as a characterised reference material related to Gemcitabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (2R,3R)-4,4-Difluoro-2-(hydroxymethyl)-5-oxotetrahydrofuran-3-yl Benzoate can I order?

We supply (2R,3R)-4,4-Difluoro-2-(hydroxymethyl)-5-oxotetrahydrofuran-3-yl Benzoate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (2R,3R)-4,4-Difluoro-2-(hydroxymethyl)-5-oxotetrahydrofuran-3-yl Benzoate?

Yes. Every lot of (2R,3R)-4,4-Difluoro-2-(hydroxymethyl)-5-oxotetrahydrofuran-3-yl Benzoate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (2R,3R)-4,4-Difluoro-2-(hydroxymethyl)-5-oxotetrahydrofuran-3-yl Benzoate be shipped internationally?

Yes. We export (2R,3R)-4,4-Difluoro-2-(hydroxymethyl)-5-oxotetrahydrofuran-3-yl Benzoate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.