(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epox… 98760-08-8

Name: (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane
Brand: Vaqora Chemicals
SKU: VQ-024384

About (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane

Vaqora Chemicals supplies (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane, an impurity of Atazanavir registered under CAS number 98760-08-8. With the molecular formula C15H21NO3, it has a molar mass of 263.33 g/mol. The IUPAC name is tert-butyl N-[(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl]carbamate. It is also known as threo-N-Boc-L-phenylalanine epoxide or (1S,2R)-Boc Epoxide.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Atazanavir, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Atazanavir

View every impurity, metabolite and intermediate we list for Atazanavir.

Atazanavir impurities

Specifications & identifiers

Chemical identifiers
Product name	(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane
Catalogue No.	VQ-024384
CAS Number	98760-08-8
IUPAC name	tert-butyl N-[(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl]carbamate
Molecular formula	C₁₅H₂₁NO₃
Molecular weight	263.33 g/mol
Exact mass	263.1521
Grade	Reference Standard
HSN code	38229090
InChIKey	NVPOUMXZERMIJK-STQMWFEESA-N
SMILES	CC(C)(C)OC(=O)N[C@@H](CC1=CC=CC=C1)[C@@H]2CO2
PubChem CID	9813904

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	1 / 3
TPSA	50.9 Å²
Synonyms	tert-Butyl ((S)-1-((R)-oxiran-2-yl)-2-phenylethyl)carbamate, tert-Butyl {(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl}carbamate, tert-butyl ((1S)-1-((2R)-oxiran-2-yl)-2-phenylethyl)carbamate, (2R,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane, (2R,3S)-3-(tert-Boc)amino-1,2-epoxy-4-phenylbutane, (2R,3S)-3-(t-BOC)amino-1,2-epoxy-4-phenylbutane, threo-N-Boc-L-phenylalanine epoxide, (2R,3S)-3-(N-BOC-amino)-1-oxirane-4-phenylbutane, tert-Butyl N-[(1S)-1-((2R)-oxiran-2-yl)-2-phenylethyl]carbamate, (1S,2R)-Boc Epoxide

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H341Suspected of causing genetic defects
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P261, P264, P270, P272, P273, P280, P301 + P317, P302 + P352, P318, P321, P330, P333 + P317, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane?

The CAS Registry Number of (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane is 98760-08-8. It is also known as tert-Butyl ((S)-1-((R)-oxiran-2-yl)-2-phenylethyl)carbamate, tert-Butyl {(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl}carbamate, tert-butyl ((1S)-1-((2R)-oxiran-2-yl)-2-phenylethyl)carbamate.

What is the molecular formula and molecular weight of (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane?

(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane has the molecular formula C15H21NO3 and a molecular weight of 263.33 g/mol. Its IUPAC name is tert-butyl N-[(1S)-1-[(2R)-oxiran-2-yl]-2-phenylethyl]carbamate.

What is (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane used for?

(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane is supplied as a characterised reference material related to Atazanavir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane can I order?

We supply (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane?

Yes. Every lot of (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane be shipped internationally?

Yes. (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.