(2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)… 172792-37-9

Name: (2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
Brand: Vaqora Chemicals
SKU: VQ-029833

About (2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol

Vaqora Chemicals supplies (2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol, a metabolite or degradation product of Cladribine registered under CAS number 172792-37-9. The compound has the formula C10H12ClN5O3, corresponding to a molecular weight of 285.69 g/mol. Systematically, it is named (2R,3S,5R)-5-(6-amino-2-chloropurin-7-yl)-2-(hydroxymethyl)oxolan-3-ol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Cladribine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer (2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Cladribine

View every impurity, metabolite and intermediate we list for Cladribine.

Cladribine impurities

Specifications & identifiers

Chemical identifiers
Product name	(2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
Catalogue No.	VQ-029833
CAS Number	172792-37-9
IUPAC name	(2R,3S,5R)-5-(6-amino-2-chloropurin-7-yl)-2-(hydroxymethyl)oxolan-3-ol
Molecular formula	C₁₀H₁₂ClN₅O₃
Molecular weight	285.69 g/mol
Exact mass	285.0629
Grade	Reference Standard
HSN code	38229090
InChIKey	NUPYICVFKFSWBB-KVQBGUIXSA-N
SMILES	C1[C@@H]([C@H](O[C@H]1N2C=NC3=NC(=NC(=C32)N)Cl)CO)O
PubChem CID	88182717

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 7
TPSA	119 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol?

The CAS Registry Number of (2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol is 172792-37-9. It is also known as (2R,3S,5R)-5-(6-amino-2-chloro-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol, 2-Chloro-7-(2-deoxy-beta-D-erythro-pentofuranosyl)-7H-purin-6-amine, 7H-Purin-6-amine, 2-chloro-7-(2-deoxy-beta-D-erythro-pentofuranosyl)-.

What is the molecular formula and molecular weight of (2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol?

(2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol has the molecular formula C10H12ClN5O3 and a molecular weight of 285.69 g/mol. Its IUPAC name is (2R,3S,5R)-5-(6-amino-2-chloropurin-7-yl)-2-(hydroxymethyl)oxolan-3-ol.

What is (2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol used for?

(2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol is supplied as a characterised reference material related to Cladribine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol can I order?

We supply (2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol?

Yes. Every lot of (2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol be shipped internationally?

Yes. We export (2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.