(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitri… 207557-35-5

Name: (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
Brand: Vaqora Chemicals
SKU: VQ-024014

About (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile

(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile is an impurity of Vildagliptin carrying the CAS registry number 207557-35-5. With the molecular formula C7H9ClN2O, it has a molar mass of 172.61 g/mol. Systematically, it is named (2S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile. It is also known as Vildagliptin Chloroacetyl Nitrile (S)-Isomer or Vildagliptin Chloroacetyl Nitrile(S)-Isomer.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Vildagliptin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Vildagliptin

View every impurity, metabolite and intermediate we list for Vildagliptin.

Vildagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
Catalogue No.	VQ-024014
CAS Number	207557-35-5
IUPAC name	(2S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile
Molecular formula	C₇H₉ClN₂O
Molecular weight	172.61 g/mol
Exact mass	172.0403
Grade	Reference Standard
HSN code	38229090
InChIKey	YCWRPKBYQZOLCD-LURJTMIESA-N
SMILES	C1C[C@H](N(C1)C(=O)CCl)C#N
PubChem CID	11073883

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	0 / 2
TPSA	44.1 Å²
Synonyms	Vildagliptin Chloroacetyl Nitrile (S)-Isomer, Vildagliptin Chloroacetyl Nitrile(S)-Isomer, (S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile, (S)-1-(2-Chloroacetyl)-pyrrolidine-2-carbonitrile, 2-Pyrrolidinecarbonitrile, 1-(2-chloroacetyl)-, (2S)-, (S)-1-(2-Chloro-acetyl)-pyrrolidine-2-carbonitrile, (2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile, (2S)-1-(chloroacetyl)pyrrolidine-2-carbonitrile, 1-(2-Chloroacetyl)pyrrolidine-2-(S)-carbonitrile, 2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-, (2S)-, (S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile, Vildagliptin Intermediate II

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P272, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile?

The CAS Registry Number of (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile is 207557-35-5. It is also known as Vildagliptin Chloroacetyl Nitrile (S)-Isomer, Vildagliptin Chloroacetyl Nitrile(S)-Isomer, (S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile.

What is the molecular formula and molecular weight of (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile?

(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile has the molecular formula C7H9ClN2O and a molecular weight of 172.61 g/mol. Its IUPAC name is (2S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile.

What is (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile used for?

(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile is supplied as a characterised reference material related to Vildagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile can I order?

We supply (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile?

Yes. Every lot of (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile be shipped internationally?

Yes. (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.