3-(4-Hydroxyphenyl)propionic acid

Name: 3-(4-Hydroxyphenyl)propionic acid
Brand: Vaqora Chemicals
SKU: VQ-029818

About 3-(4-Hydroxyphenyl)propionic acid

Listed under CAS 501-97-3, 3-(4-Hydroxyphenyl)propionic acid is a metabolite or degradation product of Esmolol available from Vaqora Chemicals. Formula C9H10O3, molecular weight 166.17 g/mol. The IUPAC name is 3-(4-hydroxyphenyl)propanoic acid. It is also known as Phloretic Acid or Hydro-p-coumaric acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Esmolol, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 3-(4-Hydroxyphenyl)propionic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Esmolol

View every impurity, metabolite and intermediate we list for Esmolol.

Esmolol impurities

Specifications & identifiers

Chemical identifiers
Product name	3-(4-Hydroxyphenyl)propionic acid
Catalogue No.	VQ-029818
CAS Number	501-97-3
IUPAC name	3-(4-hydroxyphenyl)propanoic acid
Molecular formula	C₉H₁₀O₃
Molecular weight	166.17 g/mol
Exact mass	166.063
Grade	Reference Standard
HSN code	38229090
InChIKey	NMHMNPHRMNGLLB-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1CCC(=O)O)O
PubChem CID	10394

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	2 / 3
TPSA	57.5 Å²
Synonyms	Phloretic Acid, Hydro-p-coumaric acid, Dihydro-p-coumaric acid, Benzenepropanoic acid, 4-hydroxy-, 4-Hydroxyphenylpropionic acid, p-Hydroxyhydrocinnamic acid, 3-(p-Hydroxyphenyl)propionic acid, 4-Hydroxybenzenepropanoic acid, p-Hydroxyphenylpropionic acid, Hydrocinnamic acid, p-hydroxy-, Phloretinic acid, beta-(p-Hydroxyphenyl)propionic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-(4-Hydroxyphenyl)propionic acid?

The CAS Registry Number of 3-(4-Hydroxyphenyl)propionic acid is 501-97-3. It is also known as Phloretic Acid, Hydro-p-coumaric acid, Dihydro-p-coumaric acid.

What is the molecular formula and molecular weight of 3-(4-Hydroxyphenyl)propionic acid?

3-(4-Hydroxyphenyl)propionic acid has the molecular formula C9H10O3 and a molecular weight of 166.17 g/mol. Its IUPAC name is 3-(4-hydroxyphenyl)propanoic acid.

What is 3-(4-Hydroxyphenyl)propionic acid used for?

3-(4-Hydroxyphenyl)propionic acid is supplied as a characterised reference material related to Esmolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-(4-Hydroxyphenyl)propionic acid can I order?

We supply 3-(4-Hydroxyphenyl)propionic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-(4-Hydroxyphenyl)propionic acid?

Yes. Every lot of 3-(4-Hydroxyphenyl)propionic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-(4-Hydroxyphenyl)propionic acid be shipped internationally?

Yes. 3-(4-Hydroxyphenyl)propionic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.