3-Chlorothiophene-2-carbonyl Chloride

Name: 3-Chlorothiophene-2-carbonyl Chloride
Brand: Vaqora Chemicals
SKU: VQ-049838

About 3-Chlorothiophene-2-carbonyl Chloride

3-Chlorothiophene-2-carbonyl Chloride (CAS 86427-02-3) is a process intermediate or related compound of Ramelteon offered by Vaqora Chemicals. Its molecular formula is C5H2Cl2OS and its molecular weight is 181.04 g/mol. Alternative names: 2-Thiophenecarbonyl chloride, 3-chloro- and 3-chloro-2-thiophenecarbonyl chloride.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Ramelteon, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 3-Chlorothiophene-2-carbonyl Chloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Ramelteon

View every impurity, metabolite and intermediate we list for Ramelteon.

Ramelteon impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Chlorothiophene-2-carbonyl Chloride
Catalogue No.	VQ-049838
CAS Number	86427-02-3
IUPAC name	3-chlorothiophene-2-carbonyl chloride
Molecular formula	C₅H₂Cl₂OS
Molecular weight	181.04 g/mol
Exact mass	179.9203
InChIKey	GCPHKTQMABHWPY-UHFFFAOYSA-N
SMILES	C1=CSC(=C1Cl)C(=O)Cl
PubChem CID	2735824

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	0 / 2
TPSA	45.3 Å²
Synonyms	2-Thiophenecarbonyl chloride, 3-chloro-, 3-chloro-2-thiophenecarbonyl chloride, chloro thiophene-2-carbonyl chloride, 3-chlorothiophene-2-carboyl chloride, 3-chlorothiophene-2-carbonyl chloride, AldrichCPR

Safety & hazard information (GHS)

Corrosive

Signal word: Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements: P260, P264, P280, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P321, P363, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Chlorothiophene-2-carbonyl Chloride?

The CAS Registry Number of 3-Chlorothiophene-2-carbonyl Chloride is 86427-02-3. It is also known as 2-Thiophenecarbonyl chloride, 3-chloro-, 3-chloro-2-thiophenecarbonyl chloride, chloro thiophene-2-carbonyl chloride.

What is the molecular formula and molecular weight of 3-Chlorothiophene-2-carbonyl Chloride?

3-Chlorothiophene-2-carbonyl Chloride has the molecular formula C5H2Cl2OS and a molecular weight of 181.04 g/mol. Its IUPAC name is 3-chlorothiophene-2-carbonyl chloride.

What is 3-Chlorothiophene-2-carbonyl Chloride used for?

3-Chlorothiophene-2-carbonyl Chloride is supplied as a characterised reference material related to Ramelteon. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Chlorothiophene-2-carbonyl Chloride can I order?

We supply 3-Chlorothiophene-2-carbonyl Chloride, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Chlorothiophene-2-carbonyl Chloride?

Yes. Every lot of 3-Chlorothiophene-2-carbonyl Chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Chlorothiophene-2-carbonyl Chloride be shipped internationally?

Yes. 3-Chlorothiophene-2-carbonyl Chloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.