3-Hydroxy Desloratadine

Name: 3-Hydroxy Desloratadine
Brand: Vaqora Chemicals
SKU: VQ-025251

About 3-Hydroxy Desloratadine

3-Hydroxy Desloratadine is a metabolite or degradation product of Desloratadine carrying the CAS registry number 119410-08-1. With the molecular formula C19H19ClN2O, it has a molar mass of 326.8 g/mol. Its systematic (IUPAC) name is 13-chloro-2-piperidin-4-ylidene-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-6-ol. It is also known as 3-Hydroxy Desloratadine HCl or 3-Hydroxy Desloratadine Dihydrochloride.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Desloratadine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 3-Hydroxy Desloratadine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Desloratadine

View every impurity, metabolite and intermediate we list for Desloratadine.

Desloratadine impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Hydroxy Desloratadine
Catalogue No.	VQ-025251
CAS Number	119410-08-1
IUPAC name	13-chloro-2-piperidin-4-ylidene-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-6-ol
Molecular formula	C₁₉H₁₉ClN₂O
Molecular weight	326.8 g/mol
Exact mass	326.1186
Grade	Reference Standard
HSN code	38229090
InChIKey	NDFMTPISBHBIKE-UHFFFAOYSA-N
SMILES	C1CC2=C(C(=C3CCNCC3)C4=C1C=C(C=C4)Cl)N=CC(=C2)O
PubChem CID	10359050

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	2 / 3
TPSA	45.2 Å²
Synonyms	8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-3-ol, 5H-Benzo[5,6]cyclohepta[1,2-b]pyridin-3-ol, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-, 8-chloro-11-(4-piperidinylidene)-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-3-ol, 5H-Benzo(5,6)cyclohepta(1,2-b)pyridin-3-ol, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-, 8-Chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-3-ol, 3-Hydroxy Desloratadine HCl, 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-3-ol, 3-Hydroxy Desloratadine Dihydrochloride

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H318Causes serious eye damage
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P264, P264 + P265, P270, P273, P280, P301 + P317, P305 + P354 + P338, P317, P330, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Hydroxy Desloratadine?

The CAS Registry Number of 3-Hydroxy Desloratadine is 119410-08-1. It is also known as 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-3-ol, 5H-Benzo[5,6]cyclohepta[1,2-b]pyridin-3-ol, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-, 8-chloro-11-(4-piperidinylidene)-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-3-ol.

What is the molecular formula and molecular weight of 3-Hydroxy Desloratadine?

3-Hydroxy Desloratadine has the molecular formula C19H19ClN2O and a molecular weight of 326.8 g/mol. Its IUPAC name is 13-chloro-2-piperidin-4-ylidene-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-6-ol.

What is 3-Hydroxy Desloratadine used for?

3-Hydroxy Desloratadine is supplied as a characterised reference material related to Desloratadine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Hydroxy Desloratadine can I order?

We supply 3-Hydroxy Desloratadine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Hydroxy Desloratadine?

Yes. Every lot of 3-Hydroxy Desloratadine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Hydroxy Desloratadine be shipped internationally?

Yes. 3-Hydroxy Desloratadine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.