3-[methyl(nitroso)amino]-1-(thiophen-2- yl)pr… 2418708-78-6

Name: 3-[methyl(nitroso)amino]-1-(thiophen-2- yl)propan-1-ol
Brand: Vaqora Chemicals
SKU: VQ-006796

About 3-[methyl(nitroso)amino]-1-(thiophen-2- yl)propan-1-ol

3-[methyl(nitroso)amino]-1-(thiophen-2- yl)propan-1-ol (CAS 2418708-78-6) is a nitrosamine impurity of Duloxetine offered by Vaqora Chemicals, specified at 97.8% purity. Its molecular formula is C8H12N2O2S and its molecular weight is 200.26 g/mol. The IUPAC name is N-(3-hydroxy-3-thiophen-2-ylpropyl)-N-methylnitrous amide.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Duloxetine, method validation (AMV) and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 3-[methyl(nitroso)amino]-1-(thiophen-2- yl)propan-1-ol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Duloxetine

View every impurity, metabolite and intermediate we list for Duloxetine.

Duloxetine impurities

Specifications & identifiers

Chemical identifiers
Product name	3-[methyl(nitroso)amino]-1-(thiophen-2- yl)propan-1-ol
Catalogue No.	VQ-006796
CAS Number	2418708-78-6
IUPAC name	N-(3-hydroxy-3-thiophen-2-ylpropyl)-N-methylnitrous amide
Molecular formula	C₈H₁₂N₂O₂S
Molecular weight	200.26 g/mol
Exact mass	200.0619
Grade	Reference Standard
Purity / assay	97.8%
HSN code	38229090
InChIKey	ONOOECWYKKRSAD-UHFFFAOYSA-N
SMILES	CN(CCC(C1=CC=CS1)O)N=O
PubChem CID	154577082

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	1 / 5
TPSA	81.1 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-[methyl(nitroso)amino]-1-(thiophen-2- yl)propan-1-ol?

The CAS Registry Number of 3-[methyl(nitroso)amino]-1-(thiophen-2- yl)propan-1-ol is 2418708-78-6. It is also known as α-[2-(Methylnitrosoamino)ethyl]-2-thiophenemethanol, 3-[methyl(nitroso)amino]-1-(thiophen-2- yl)propan-1-ol(Mixture of Diastereomers), N-(3-hydroxy-3-(thiophen-2-yl)propyl)-N-methylnitrous amide.

What is the molecular formula and molecular weight of 3-[methyl(nitroso)amino]-1-(thiophen-2- yl)propan-1-ol?

3-[methyl(nitroso)amino]-1-(thiophen-2- yl)propan-1-ol has the molecular formula C8H12N2O2S and a molecular weight of 200.26 g/mol. Its IUPAC name is N-(3-hydroxy-3-thiophen-2-ylpropyl)-N-methylnitrous amide.

What is 3-[methyl(nitroso)amino]-1-(thiophen-2- yl)propan-1-ol used for?

3-[methyl(nitroso)amino]-1-(thiophen-2- yl)propan-1-ol is supplied as a characterised reference material related to Duloxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-[methyl(nitroso)amino]-1-(thiophen-2- yl)propan-1-ol can I order?

We supply 3-[methyl(nitroso)amino]-1-(thiophen-2- yl)propan-1-ol in Reference Standard (97.8%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-[methyl(nitroso)amino]-1-(thiophen-2- yl)propan-1-ol?

Yes. Every lot of 3-[methyl(nitroso)amino]-1-(thiophen-2- yl)propan-1-ol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-[methyl(nitroso)amino]-1-(thiophen-2- yl)propan-1-ol be shipped internationally?

Yes. We export 3-[methyl(nitroso)amino]-1-(thiophen-2- yl)propan-1-ol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.