3-O-Desmethyl Amlodipine

Name: 3-O-Desmethyl Amlodipine
Brand: Vaqora Chemicals
SKU: VQ-021561

About 3-O-Desmethyl Amlodipine

Vaqora Chemicals supplies 3-O-Desmethyl Amlodipine, a metabolite or degradation product of Amlodipine registered under CAS number 113994-37-9. Formula C19H23ClN2O5, molecular weight 394.8 g/mol. Its systematic (IUPAC) name is 6-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-5-ethoxycarbonyl-2-methyl-1,4-dihydropyridine-3-carboxylic acid. Alternative names: Desmethyl Amlodipine and Desmethyl amolodipine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Amlodipine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 3-O-Desmethyl Amlodipine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Amlodipine

View every impurity, metabolite and intermediate we list for Amlodipine.

Amlodipine impurities

Specifications & identifiers

Chemical identifiers
Product name	3-O-Desmethyl Amlodipine
Catalogue No.	VQ-021561
CAS Number	113994-37-9
IUPAC name	6-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-5-ethoxycarbonyl-2-methyl-1,4-dihydropyridine-3-carboxylic acid
Molecular formula	C₁₉H₂₃ClN₂O₅
Molecular weight	394.8 g/mol
Exact mass	394.1295
Grade	Reference Standard
HSN code	38229090
InChIKey	RMMLXNROVBYURX-UHFFFAOYSA-N
SMILES	CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)O)C)COCCN
PubChem CID	14271883

Physical properties
Physical form	Solid
LogP (XLogP3)	0.4
H-bond donors / acceptors	3 / 7
TPSA	111 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-O-Desmethyl Amlodipine?

The CAS Registry Number of 3-O-Desmethyl Amlodipine is 113994-37-9. It is also known as Desmethyl Amlodipine, Desmethyl amolodipine, Desmethylamolodipine (M6).

What is the molecular formula and molecular weight of 3-O-Desmethyl Amlodipine?

3-O-Desmethyl Amlodipine has the molecular formula C19H23ClN2O5 and a molecular weight of 394.8 g/mol. Its IUPAC name is 6-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-5-ethoxycarbonyl-2-methyl-1,4-dihydropyridine-3-carboxylic acid.

What is 3-O-Desmethyl Amlodipine used for?

3-O-Desmethyl Amlodipine is supplied as a characterised reference material related to Amlodipine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-O-Desmethyl Amlodipine can I order?

We supply 3-O-Desmethyl Amlodipine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-O-Desmethyl Amlodipine?

Yes. Every lot of 3-O-Desmethyl Amlodipine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-O-Desmethyl Amlodipine be shipped internationally?

Yes. We export 3-O-Desmethyl Amlodipine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.