3-Phenylphthalide

Name: 3-Phenylphthalide
Brand: Vaqora Chemicals
SKU: VQ-038578

About 3-Phenylphthalide

Listed under CAS 5398-11-8, 3-Phenylphthalide is an impurity of Nefopam available from Vaqora Chemicals. With the molecular formula C14H10O2, it has a molar mass of 210.23 g/mol. The IUPAC name is 3-phenyl-3H-2-benzofuran-1-one. Common synonyms include 3-Phenylisobenzofuran-1(3H)-one and 3-phenyl-1,3-dihydro-2-benzofuran-1-one.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Nefopam, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 3-Phenylphthalide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nefopam

View every impurity, metabolite and intermediate we list for Nefopam.

Nefopam impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Phenylphthalide
Catalogue No.	VQ-038578
CAS Number	5398-11-8
IUPAC name	3-phenyl-3H-2-benzofuran-1-one
Molecular formula	C₁₄H₁₀O₂
Molecular weight	210.23 g/mol
Exact mass	210.0681
Grade	Reference Standard
HSN code	38229090
InChIKey	SQFMIHCARVMICF-UHFFFAOYSA-N
SMILES	C1=CC=C(C=C1)C2C3=CC=CC=C3C(=O)O2
PubChem CID	95365

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	0 / 2
TPSA	26.3 Å²
Synonyms	3-Phenylisobenzofuran-1(3H)-one, 3-phenyl-1,3-dihydro-2-benzofuran-1-one, 3-phenyl-2-benzofuran-1(3H)-one, 1(3H)-Isobenzofuranone, 3-phenyl-, Phthalide, 3-phenyl-, 3-phenyl-3H-isobenzofuran-1-one, 3-phenyl-3-hydroisobenzofuran-1-one, 3-Phenyl-1(3H)-isobenzofuranone, (S)-3-Phenylisobenzofuran-1(3H)-one, 1-phenylisobenzofuran-3-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Phenylphthalide?

The CAS Registry Number of 3-Phenylphthalide is 5398-11-8. It is also known as 3-Phenylisobenzofuran-1(3H)-one, 3-phenyl-1,3-dihydro-2-benzofuran-1-one, 3-phenyl-2-benzofuran-1(3H)-one.

What is the molecular formula and molecular weight of 3-Phenylphthalide?

3-Phenylphthalide has the molecular formula C14H10O2 and a molecular weight of 210.23 g/mol. Its IUPAC name is 3-phenyl-3H-2-benzofuran-1-one.

What is 3-Phenylphthalide used for?

3-Phenylphthalide is supplied as a characterised reference material related to Nefopam. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Phenylphthalide can I order?

We supply 3-Phenylphthalide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Phenylphthalide?

Yes. Every lot of 3-Phenylphthalide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Phenylphthalide be shipped internationally?

Yes. 3-Phenylphthalide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.