3-Piperazin-1-ylbenzo(d)isothiazole 1,1-dioxi… 131540-88-0

Name: 3-Piperazin-1-ylbenzo(d)isothiazole 1,1-dioxide
Brand: Vaqora Chemicals
SKU: VQ-044361

About 3-Piperazin-1-ylbenzo(d)isothiazole 1,1-dioxide

Listed under CAS 131540-88-0, 3-Piperazin-1-ylbenzo(d)isothiazole 1,1-dioxide is an impurity of Ziprasidone available from Vaqora Chemicals. Formula C11H13N3O2S, molecular weight 251.31 g/mol. Its systematic (IUPAC) name is 3-piperazin-1-yl-1,2-benzothiazole 1,1-dioxide. Common synonyms include Ziprasidone (m1) and Bitp-SO2.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Ziprasidone impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 3-Piperazin-1-ylbenzo(d)isothiazole 1,1-dioxide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ziprasidone

View every impurity, metabolite and intermediate we list for Ziprasidone.

Ziprasidone impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Piperazin-1-ylbenzo(d)isothiazole 1,1-dioxide
Catalogue No.	VQ-044361
CAS Number	131540-88-0
IUPAC name	3-piperazin-1-yl-1,2-benzothiazole 1,1-dioxide
Molecular formula	C₁₁H₁₃N₃O₂S
Molecular weight	251.31 g/mol
Exact mass	251.0728
Grade	Reference Standard
HSN code	38229090
InChIKey	JPBXIPJNXUMSSQ-UHFFFAOYSA-N
SMILES	C1CN(CCN1)C2=NS(=O)(=O)C3=CC=CC=C32
PubChem CID	695718

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.3
H-bond donors / acceptors	1 / 4
TPSA	70.2 Å²
Synonyms	1,2-Benzisothiazole, 3-(1-piperazinyl)-, 1,1-dioxide, 3-(Piperazin-1-yl)-1,2-benzothiazole-1,1-dione, Ziprasidone (m1), Bitp-SO2, 3-(piperazin-1-yl)-1lambda6,2-benzothiazole-1,1-dione, Benzisothiazole-3Yl-Piperazine Sulfoxide, 1-(1,1-dioxo-1,2-benzisothiazol-3-yl)piperazine, 3-(Piperazin-1-yl)-1, E6,2-benzothiazole-1,1-dione

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Piperazin-1-ylbenzo(d)isothiazole 1,1-dioxide?

The CAS Registry Number of 3-Piperazin-1-ylbenzo(d)isothiazole 1,1-dioxide is 131540-88-0. It is also known as 1,2-Benzisothiazole, 3-(1-piperazinyl)-, 1,1-dioxide, 3-(Piperazin-1-yl)-1,2-benzothiazole-1,1-dione, Ziprasidone (m1).

What is the molecular formula and molecular weight of 3-Piperazin-1-ylbenzo(d)isothiazole 1,1-dioxide?

3-Piperazin-1-ylbenzo(d)isothiazole 1,1-dioxide has the molecular formula C11H13N3O2S and a molecular weight of 251.31 g/mol. Its IUPAC name is 3-piperazin-1-yl-1,2-benzothiazole 1,1-dioxide.

What is 3-Piperazin-1-ylbenzo(d)isothiazole 1,1-dioxide used for?

3-Piperazin-1-ylbenzo(d)isothiazole 1,1-dioxide is supplied as a characterised reference material related to Ziprasidone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Piperazin-1-ylbenzo(d)isothiazole 1,1-dioxide can I order?

We supply 3-Piperazin-1-ylbenzo(d)isothiazole 1,1-dioxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Piperazin-1-ylbenzo(d)isothiazole 1,1-dioxide?

Yes. Every lot of 3-Piperazin-1-ylbenzo(d)isothiazole 1,1-dioxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Piperazin-1-ylbenzo(d)isothiazole 1,1-dioxide be shipped internationally?

Yes. 3-Piperazin-1-ylbenzo(d)isothiazole 1,1-dioxide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.