3,3-Pentamethylene-2-pyrrolidinone

Name: 3,3-Pentamethylene-2-pyrrolidinone
Brand: Vaqora Chemicals
SKU: VQ-048494

About 3,3-Pentamethylene-2-pyrrolidinone

3,3-Pentamethylene-2-pyrrolidinone (CAS 1005-85-2) is an impurity of Gabapentin offered by Vaqora Chemicals. The compound has the formula C9H15NO, corresponding to a molecular weight of 153.22 g/mol. Systematically, it is named 2-azaspiro[4.5]decan-1-one. Alternative names: 2-Azaspiro(4.5)decan-1-one and 2-azaspiro[4.5]deca-1-one.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Gabapentin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Gabapentin

View every impurity, metabolite and intermediate we list for Gabapentin.

Gabapentin impurities

Specifications & identifiers

Chemical identifiers
Product name	3,3-Pentamethylene-2-pyrrolidinone
Catalogue No.	VQ-048494
CAS Number	1005-85-2
IUPAC name	2-azaspiro[4.5]decan-1-one
Molecular formula	C₉H₁₅NO
Molecular weight	153.22 g/mol
Exact mass	153.1154
Grade	Reference Standard
HSN code	38229090
InChIKey	UYZFAPXBVNFJFD-UHFFFAOYSA-N
SMILES	C1CCC2(CC1)CCNC2=O
PubChem CID	25067265

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	1 / 1
TPSA	29.1 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3,3-Pentamethylene-2-pyrrolidinone?

The CAS Registry Number of 3,3-Pentamethylene-2-pyrrolidinone is 1005-85-2. It is also known as 2-Azaspiro(4.5)decan-1-one, 2-azaspiro[4.5]deca-1-one, 2-Aza-spiro[4.5]decan-1-one.

What is the molecular formula and molecular weight of 3,3-Pentamethylene-2-pyrrolidinone?

3,3-Pentamethylene-2-pyrrolidinone has the molecular formula C9H15NO and a molecular weight of 153.22 g/mol. Its IUPAC name is 2-azaspiro[4.5]decan-1-one.

What is 3,3-Pentamethylene-2-pyrrolidinone used for?

3,3-Pentamethylene-2-pyrrolidinone is supplied as a characterised reference material related to Gabapentin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3,3-Pentamethylene-2-pyrrolidinone can I order?

We supply 3,3-Pentamethylene-2-pyrrolidinone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3,3-Pentamethylene-2-pyrrolidinone?

Yes. Every lot of 3,3-Pentamethylene-2-pyrrolidinone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3,3-Pentamethylene-2-pyrrolidinone be shipped internationally?

Yes. 3,3-Pentamethylene-2-pyrrolidinone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.