3,5-Anhydrothymidine

Name: 3,5-Anhydrothymidine
Brand: Vaqora Chemicals
SKU: VQ-032504

About 3,5-Anhydrothymidine

3,5-Anhydrothymidine is an impurity of Stavudine carrying the CAS registry number 38313-48-3. The compound has the formula C10H12N2O4, corresponding to a molecular weight of 224.21 g/mol. Its systematic (IUPAC) name is 1-[(1R,3R,5S)-2,6-dioxabicyclo[3.2.0]heptan-3-yl]-5-methylpyrimidine-2,4-dione. Common synonyms include Thymidine, 3',5'-anhydro- and 2,5'-Anhydro-thymidine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Stavudine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 3,5-Anhydrothymidine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Stavudine

View every impurity, metabolite and intermediate we list for Stavudine.

Stavudine impurities

Specifications & identifiers

Chemical identifiers
Product name	3,5-Anhydrothymidine
Catalogue No.	VQ-032504
CAS Number	38313-48-3
IUPAC name	1-[(1R,3R,5S)-2,6-dioxabicyclo[3.2.0]heptan-3-yl]-5-methylpyrimidine-2,4-dione
Molecular formula	C₁₀H₁₂N₂O₄
Molecular weight	224.21 g/mol
Exact mass	224.0797
Grade	Reference Standard
HSN code	38229090
InChIKey	OAWLMYIJZBBZTP-XLPZGREQSA-N
SMILES	CC1=CN(C(=O)NC1=O)[C@H]2C[C@H]3[C@H](O2)CO3
PubChem CID	14069470

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.5
H-bond donors / acceptors	1 / 4
TPSA	67.9 Å²

Safety & hazard information (GHS)

Hazard statements

H412Harmful to aquatic life with long lasting effects

Precautionary statements: P273, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3,5-Anhydrothymidine?

The CAS Registry Number of 3,5-Anhydrothymidine is 38313-48-3. It is also known as Thymidine, 3',5'-anhydro-, 2,5'-Anhydro-thymidine, 1-[(1R,3R,5S)-2,6-dioxabicyclo[3.2.0]heptan-3-yl]-5-methyl-pyrimidine-2,4-dione.

What is the molecular formula and molecular weight of 3,5-Anhydrothymidine?

3,5-Anhydrothymidine has the molecular formula C10H12N2O4 and a molecular weight of 224.21 g/mol. Its IUPAC name is 1-[(1R,3R,5S)-2,6-dioxabicyclo[3.2.0]heptan-3-yl]-5-methylpyrimidine-2,4-dione.

What is 3,5-Anhydrothymidine used for?

3,5-Anhydrothymidine is supplied as a characterised reference material related to Stavudine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3,5-Anhydrothymidine can I order?

We supply 3,5-Anhydrothymidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3,5-Anhydrothymidine?

Yes. Every lot of 3,5-Anhydrothymidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3,5-Anhydrothymidine be shipped internationally?

Yes. We export 3,5-Anhydrothymidine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.