(3R,5R)-Rosuvastatin Lactone

Name: (3R,5R)-Rosuvastatin Lactone
Brand: Vaqora Chemicals
SKU: VQ-023675

About (3R,5R)-Rosuvastatin Lactone

(3R,5R)-Rosuvastatin Lactone (CAS 1422954-11-7) is an impurity of Rosuvastatin offered by Vaqora Chemicals. Formula C22H26FN3O5S, molecular weight 463.5 g/mol. Common synonyms include Rosuvastatin (3R,5R)-Lactone and (3R,5R)-Rosuvastatin Lactone (Free Base).

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Rosuvastatin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (3R,5R)-Rosuvastatin Lactone in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Rosuvastatin

View every impurity, metabolite and intermediate we list for Rosuvastatin.

Rosuvastatin impurities

Specifications & identifiers

Chemical identifiers
Product name	(3R,5R)-Rosuvastatin Lactone
Catalogue No.	VQ-023675
CAS Number	1422954-11-7
IUPAC name	N-[4-(4-fluorophenyl)-5-[(E)-2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethenyl]-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide
Molecular formula	C₂₂H₂₆FN₃O₅S
Molecular weight	463.5 g/mol
Exact mass	463.1577
Grade	Reference Standard
HSN code	38229090
InChIKey	SOEGVMSNJOCVHT-ZUQFGZKASA-N
SMILES	CC(C)C1=NC(=NC(=C1/C=C/[C@H]2C[C@H](CC(=O)O2)O)C3=CC=C(C=C3)F)N(C)S(=O)(=O)C
PubChem CID	29918987

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	1 / 9
TPSA	118 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (3R,5R)-Rosuvastatin Lactone?

The CAS Registry Number of (3R,5R)-Rosuvastatin Lactone is 1422954-11-7. It is also known as Rosuvastatin (3R,5R)-Lactone, (3R,5R)-Rosuvastatin Lactone (Free Base).

What is the molecular formula and molecular weight of (3R,5R)-Rosuvastatin Lactone?

(3R,5R)-Rosuvastatin Lactone has the molecular formula C22H26FN3O5S and a molecular weight of 463.5 g/mol. Its IUPAC name is N-[4-(4-fluorophenyl)-5-[(E)-2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethenyl]-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide.

What is (3R,5R)-Rosuvastatin Lactone used for?

(3R,5R)-Rosuvastatin Lactone is supplied as a characterised reference material related to Rosuvastatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (3R,5R)-Rosuvastatin Lactone can I order?

We supply (3R,5R)-Rosuvastatin Lactone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (3R,5R)-Rosuvastatin Lactone?

Yes. Every lot of (3R,5R)-Rosuvastatin Lactone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (3R,5R)-Rosuvastatin Lactone be shipped internationally?

Yes. We export (3R,5R)-Rosuvastatin Lactone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.