(3S)-Aminoquinuclidine Dihydrochloride

Name: (3S)-Aminoquinuclidine Dihydrochloride
Brand: Vaqora Chemicals
SKU: VQ-039110

About (3S)-Aminoquinuclidine Dihydrochloride

Vaqora Chemicals supplies (3S)-Aminoquinuclidine Dihydrochloride, an impurity of Palonosetron registered under CAS number 119904-90-4. Formula C7H16Cl2N2, molecular weight 199.12 g/mol. Common synonyms include (S)-3-Aminoquinuclidine dihydrochloride and (S)-Quinuclidin-3-amine dihydrochloride.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Palonosetron to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (3S)-Aminoquinuclidine Dihydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Palonosetron

View every impurity, metabolite and intermediate we list for Palonosetron.

Palonosetron impurities

Specifications & identifiers

Chemical identifiers
Product name	(3S)-Aminoquinuclidine Dihydrochloride
Catalogue No.	VQ-039110
CAS Number	119904-90-4
IUPAC name	(3S)-1-azabicyclo[2.2.2]octan-3-amine;dihydrochloride
Molecular formula	C₇H₁₆Cl₂N₂
Molecular weight	199.12 g/mol
Exact mass	198.0691
Grade	Reference Standard
HSN code	38229090
InChIKey	STZHBULOYDCZET-XCUBXKJBSA-N
SMILES	C1CN2CCC1[C@@H](C2)N.Cl.Cl
PubChem CID	12494973

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 2
TPSA	29.3 Å²
Synonyms	(3S)-1-azabicyclo[2.2.2]octan-3-amine dihydrochloride, (3S)-1-azabicyclo(2.2.2)octan-3-amine dihydrochloride, (S)-3-Aminoquinuclidine dihydrochloride, (S)-Quinuclidin-3-amine dihydrochloride, (S)-(-)-3-Aminoquinuclidine dihydrochloride, (S)-(-)-3-Aminoquinuclidine 2HCl, (S)-Quinuclidin-3-amine (dihydrochloride), 1-Azabicyclo[2.2.2]octan-3-amine, dihydrochloride, (3S)-, S-(-)-3-Aminoquinuclidine dihydrochloride, (S)-(-)-3-Amino-1-azabicyclo[2.2.2]octane Dihydrochloride, (S)-quinuclidin-3-amine 2HCl, CS-M1833

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (3S)-Aminoquinuclidine Dihydrochloride?

The CAS Registry Number of (3S)-Aminoquinuclidine Dihydrochloride is 119904-90-4. It is also known as (3S)-1-azabicyclo[2.2.2]octan-3-amine dihydrochloride, (3S)-1-azabicyclo(2.2.2)octan-3-amine dihydrochloride, (S)-3-Aminoquinuclidine dihydrochloride.

What is the molecular formula and molecular weight of (3S)-Aminoquinuclidine Dihydrochloride?

(3S)-Aminoquinuclidine Dihydrochloride has the molecular formula C7H16Cl2N2 and a molecular weight of 199.12 g/mol.

What is (3S)-Aminoquinuclidine Dihydrochloride used for?

(3S)-Aminoquinuclidine Dihydrochloride is supplied as a characterised reference material related to Palonosetron. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (3S)-Aminoquinuclidine Dihydrochloride can I order?

We supply (3S)-Aminoquinuclidine Dihydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (3S)-Aminoquinuclidine Dihydrochloride?

Yes. Every lot of (3S)-Aminoquinuclidine Dihydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (3S)-Aminoquinuclidine Dihydrochloride be shipped internationally?

Yes. (3S)-Aminoquinuclidine Dihydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.