(3S,4S)-4-[(R)-1-Carboxyethyl]-3-[(R)-1-(t-bu… 90776-58-2

Name: (3S,4S)-4-[(R)-1-Carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone
Brand: Vaqora Chemicals
SKU: VQ-043698

About (3S,4S)-4-[(R)-1-Carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone

Vaqora Chemicals supplies (3S,4S)-4-[(R)-1-Carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone, an impurity of Meropenem registered under CAS number 90776-58-2. Formula C14H27NO4Si, molecular weight 301.45 g/mol. Its systematic (IUPAC) name is (2R)-2-[(2S,3S)-3-[(1R)-1-[tert-butyl(dimethyl)silyl]oxyethyl]-4-oxoazetidin-2-yl]propanoic acid. Alternative names: 4bma and beta-Methylazetidin-2-one.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Meropenem to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer (3S,4S)-4-[(R)-1-Carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Meropenem

View every impurity, metabolite and intermediate we list for Meropenem.

Meropenem impurities

Specifications & identifiers

Chemical identifiers
Product name	(3S,4S)-4-[(R)-1-Carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone
Catalogue No.	VQ-043698
CAS Number	90776-58-2
IUPAC name	(2R)-2-[(2S,3S)-3-[(1R)-1-[tert-butyl(dimethyl)silyl]oxyethyl]-4-oxoazetidin-2-yl]propanoic acid
Molecular formula	C₁₄H₂₇NO₄Si
Molecular weight	301.45 g/mol
Exact mass	301.1709
Grade	Reference Standard
HSN code	38229090
InChIKey	NNANGMFTFSNDLW-GWOFURMSSA-N
SMILES	C[C@H]([C@@H]1[C@H](NC1=O)[C@@H](C)C(=O)O)O[Si](C)(C)C(C)(C)C
PubChem CID	9882831

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 4
TPSA	75.6 Å²
Synonyms	(3S 4S)-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-4-[(R)-1-carboxyethyl]-2-azetidinone, (3S,4S)-3-[(R)-1-(tert-Butyldimethylsilyloxy)ethyl]-4-[(R)-1-carboxyethyl]-2-azetidinone, (3S,4S)-3-((R)-(tert-Butyldimethyl-silyloxy)ethyl)-4((R)-carboxyethyl)-2-azetidinone, 4bma, beta-Methylazetidin-2-one, (3s 4s)-3-[ (r)-1-(t-butyldimethylsilyloxy)ethyl]-4[(r)-1-carboxyethyl]-2-azetidinone, (3S ,4S)-3-[(1R)-1-t-Butyldimethylsilyloxyethyl]-4-[(1R)-1-carboxyethyl]-2-azetidinone, (3S,4S)-3-[(1R)-1-t-Butyldimethylsilyloxyethyl]-4-[(1R)-1-carboxyethyl]-2-azetidinone, 4-[(R)-1-carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone, (3S,4S)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (3S,4S)-4-[(R)-1-Carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone?

The CAS Registry Number of (3S,4S)-4-[(R)-1-Carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone is 90776-58-2. It is also known as (3S 4S)-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-4-[(R)-1-carboxyethyl]-2-azetidinone, (3S,4S)-3-[(R)-1-(tert-Butyldimethylsilyloxy)ethyl]-4-[(R)-1-carboxyethyl]-2-azetidinone, (3S,4S)-3-((R)-(tert-Butyldimethyl-silyloxy)ethyl)-4((R)-carboxyethyl)-2-azetidinone.

What is the molecular formula and molecular weight of (3S,4S)-4-[(R)-1-Carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone?

(3S,4S)-4-[(R)-1-Carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone has the molecular formula C14H27NO4Si and a molecular weight of 301.45 g/mol. Its IUPAC name is (2R)-2-[(2S,3S)-3-[(1R)-1-[tert-butyl(dimethyl)silyl]oxyethyl]-4-oxoazetidin-2-yl]propanoic acid.

What is (3S,4S)-4-[(R)-1-Carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone used for?

(3S,4S)-4-[(R)-1-Carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone is supplied as a characterised reference material related to Meropenem. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (3S,4S)-4-[(R)-1-Carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone can I order?

We supply (3S,4S)-4-[(R)-1-Carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (3S,4S)-4-[(R)-1-Carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone?

Yes. Every lot of (3S,4S)-4-[(R)-1-Carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (3S,4S)-4-[(R)-1-Carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone be shipped internationally?

Yes. We export (3S,4S)-4-[(R)-1-Carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.