4-2R,3S,4S,5R)-3-(3,4-Difluoro- 2-hydroxyphen… 2649467-91-2

Name: 4-2R,3S,4S,5R)-3-(3,4-Difluoro- 2-hydroxyphenyl)tetrahydro- 4,5-dimethyl-5-(trifluoromethyl)- 2-furanyl]carbonyl]amino]-2- Pyridinecarboxamide
Brand: Vaqora Chemicals
SKU: VQ-028162

About 4-2R,3S,4S,5R)-3-(3,4-Difluoro- 2-hydroxyphenyl)tetrahydro- 4,5-dimethyl-5-(trifluoromethyl)- 2-furanyl]carbonyl]amino]-2- Pyridinecarboxamide

Listed under CAS 2649467-91-2, 4-2R,3S,4S,5R)-3-(3,4-Difluoro- 2-hydroxyphenyl)tetrahydro- 4,5-dimethyl-5-(trifluoromethyl)- 2-furanyl]carbonyl]amino]-2- Pyridinecarboxamide is a metabolite or degradation product of Suzetrigine available from Vaqora Chemicals. The compound has the formula C20H18F5N3O4, corresponding to a molecular weight of 459.4 g/mol. Common synonyms include Suzetrigine phenol and EX-A9086.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Suzetrigine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Suzetrigine

View every impurity, metabolite and intermediate we list for Suzetrigine.

Suzetrigine impurities

Specifications & identifiers

Chemical identifiers
Product name	4-2R,3S,4S,5R)-3-(3,4-Difluoro- 2-hydroxyphenyl)tetrahydro- 4,5-dimethyl-5-(trifluoromethyl)- 2-furanyl]carbonyl]amino]-2- Pyridinecarboxamide
Catalogue No.	VQ-028162
CAS Number	2649467-91-2
IUPAC name	4-[[(2R,3S,4S,5R)-3-(3,4-difluoro-2-hydroxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)oxolane-2-carbonyl]amino]pyridine-2-carboxamide
Molecular formula	C₂₀H₁₈F₅N₃O₄
Molecular weight	459.4 g/mol
Exact mass	459.1217
Grade	Reference Standard
HSN code	38229090
InChIKey	WHNITIVOSUKTKC-CFKRIXOTSA-N
SMILES	C[C@H]1[C@H]([C@@H](O[C@@]1(C)C(F)(F)F)C(=O)NC2=CC(=NC=C2)C(=O)N)C3=C(C(=C(C=C3)F)F)O
PubChem CID	156444660

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	3 / 10
TPSA	115 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-2R,3S,4S,5R)-3-(3,4-Difluoro- 2-hydroxyphenyl)tetrahydro- 4,5-dimethyl-5-(trifluoromethyl)- 2-furanyl]carbonyl]amino]-2- Pyridinecarboxamide?

The CAS Registry Number of 4-2R,3S,4S,5R)-3-(3,4-Difluoro- 2-hydroxyphenyl)tetrahydro- 4,5-dimethyl-5-(trifluoromethyl)- 2-furanyl]carbonyl]amino]-2- Pyridinecarboxamide is 2649467-91-2. It is also known as Suzetrigine phenol, EX-A9086.

What is the molecular formula and molecular weight of 4-2R,3S,4S,5R)-3-(3,4-Difluoro- 2-hydroxyphenyl)tetrahydro- 4,5-dimethyl-5-(trifluoromethyl)- 2-furanyl]carbonyl]amino]-2- Pyridinecarboxamide?

4-2R,3S,4S,5R)-3-(3,4-Difluoro- 2-hydroxyphenyl)tetrahydro- 4,5-dimethyl-5-(trifluoromethyl)- 2-furanyl]carbonyl]amino]-2- Pyridinecarboxamide has the molecular formula C20H18F5N3O4 and a molecular weight of 459.4 g/mol. Its IUPAC name is 4-[[(2R,3S,4S,5R)-3-(3,4-difluoro-2-hydroxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)oxolane-2-carbonyl]amino]pyridine-2-carboxamide.

What is 4-2R,3S,4S,5R)-3-(3,4-Difluoro- 2-hydroxyphenyl)tetrahydro- 4,5-dimethyl-5-(trifluoromethyl)- 2-furanyl]carbonyl]amino]-2- Pyridinecarboxamide used for?

4-2R,3S,4S,5R)-3-(3,4-Difluoro- 2-hydroxyphenyl)tetrahydro- 4,5-dimethyl-5-(trifluoromethyl)- 2-furanyl]carbonyl]amino]-2- Pyridinecarboxamide is supplied as a characterised reference material related to Suzetrigine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-2R,3S,4S,5R)-3-(3,4-Difluoro- 2-hydroxyphenyl)tetrahydro- 4,5-dimethyl-5-(trifluoromethyl)- 2-furanyl]carbonyl]amino]-2- Pyridinecarboxamide can I order?

We supply 4-2R,3S,4S,5R)-3-(3,4-Difluoro- 2-hydroxyphenyl)tetrahydro- 4,5-dimethyl-5-(trifluoromethyl)- 2-furanyl]carbonyl]amino]-2- Pyridinecarboxamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-2R,3S,4S,5R)-3-(3,4-Difluoro- 2-hydroxyphenyl)tetrahydro- 4,5-dimethyl-5-(trifluoromethyl)- 2-furanyl]carbonyl]amino]-2- Pyridinecarboxamide?

Yes. Every lot of 4-2R,3S,4S,5R)-3-(3,4-Difluoro- 2-hydroxyphenyl)tetrahydro- 4,5-dimethyl-5-(trifluoromethyl)- 2-furanyl]carbonyl]amino]-2- Pyridinecarboxamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-2R,3S,4S,5R)-3-(3,4-Difluoro- 2-hydroxyphenyl)tetrahydro- 4,5-dimethyl-5-(trifluoromethyl)- 2-furanyl]carbonyl]amino]-2- Pyridinecarboxamide be shipped internationally?

Yes. We export 4-2R,3S,4S,5R)-3-(3,4-Difluoro- 2-hydroxyphenyl)tetrahydro- 4,5-dimethyl-5-(trifluoromethyl)- 2-furanyl]carbonyl]amino]-2- Pyridinecarboxamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.