4-((3-Chloro-4-methoxybenzyl)amino)-2-(methyl… 330786-34-0

Name: 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid
Brand: Vaqora Chemicals
SKU: VQ-043061

About 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid

4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid is an impurity of Avanafil carrying the CAS registry number 330786-34-0. With the molecular formula C14H14ClN3O3S, it has a molar mass of 339.8 g/mol. Its systematic (IUPAC) name is 4-[(3-chloro-4-methoxyphenyl)methylamino]-2-methylsulfanylpyrimidine-5-carboxylic acid. Common synonyms include Avanafil RC 6.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Avanafil, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Avanafil

View every impurity, metabolite and intermediate we list for Avanafil.

Avanafil impurities

Specifications & identifiers

Chemical identifiers
Product name	4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid
Catalogue No.	VQ-043061
CAS Number	330786-34-0
IUPAC name	4-[(3-chloro-4-methoxyphenyl)methylamino]-2-methylsulfanylpyrimidine-5-carboxylic acid
Molecular formula	C₁₄H₁₄ClN₃O₃S
Molecular weight	339.8 g/mol
Exact mass	339.0444
Grade	Reference Standard
HSN code	38229090
InChIKey	PXYYGISXAWKTCT-UHFFFAOYSA-N
SMILES	COC1=C(C=C(C=C1)CNC2=NC(=NC=C2C(=O)O)SC)Cl
PubChem CID	22665572

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	2 / 7
TPSA	110 Å²
Synonyms	Avanafil RC 6, 2-methylthio-4-(3-chloro-4-methoxybenzyl-amino)-5-carboxypyrimidine, 2-methylthio-4-(3-chloro-4-methoxybenzylamino)-5-carboxypyrimidine, 4-[(3-chloro-4-methoxy-phenyl)methylamino]-2-methylsulfanyl-pyrimidine-5-carboxylic acid, 4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylsulfanyl)pyrimidine-5-carboxylic acid, 5-Pyrimidinecarboxylic acid, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid?

The CAS Registry Number of 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid is 330786-34-0. It is also known as Avanafil RC 6, 2-methylthio-4-(3-chloro-4-methoxybenzyl-amino)-5-carboxypyrimidine, 2-methylthio-4-(3-chloro-4-methoxybenzylamino)-5-carboxypyrimidine.

What is the molecular formula and molecular weight of 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid?

4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid has the molecular formula C14H14ClN3O3S and a molecular weight of 339.8 g/mol. Its IUPAC name is 4-[(3-chloro-4-methoxyphenyl)methylamino]-2-methylsulfanylpyrimidine-5-carboxylic acid.

What is 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid used for?

4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid is supplied as a characterised reference material related to Avanafil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid can I order?

We supply 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid?

Yes. Every lot of 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid be shipped internationally?

Yes. We export 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.