4-(3-Chlorophenyl)-1-nitrosopiperazine

Name: 4-(3-Chlorophenyl)-1-nitrosopiperazine
Brand: Vaqora Chemicals
SKU: VQ-028486

About 4-(3-Chlorophenyl)-1-nitrosopiperazine

4-(3-Chlorophenyl)-1-nitrosopiperazine is a nitrosamine impurity of Trazodone carrying the CAS registry number 2219339-13-4. Its molecular formula is C10H12ClN3O and its molecular weight is 225.67 g/mol. The IUPAC name is 1-(3-chlorophenyl)-4-nitrosopiperazine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Trazodone, method validation (AMV) and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-(3-Chlorophenyl)-1-nitrosopiperazine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Trazodone

View every impurity, metabolite and intermediate we list for Trazodone.

Trazodone impurities

Specifications & identifiers

Chemical identifiers
Product name	4-(3-Chlorophenyl)-1-nitrosopiperazine
Catalogue No.	VQ-028486
CAS Number	2219339-13-4
IUPAC name	1-(3-chlorophenyl)-4-nitrosopiperazine
Molecular formula	C₁₀H₁₂ClN₃O
Molecular weight	225.67 g/mol
Exact mass	225.0669
Grade	Reference Standard
HSN code	38229090
InChIKey	SAUUWOYGFFSLAY-UHFFFAOYSA-N
SMILES	C1CN(CCN1C2=CC(=CC=C2)Cl)N=O
PubChem CID	155819595

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	0 / 4
TPSA	35.9 Å²

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H351Suspected of causing cancer

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-(3-Chlorophenyl)-1-nitrosopiperazine?

The CAS Registry Number of 4-(3-Chlorophenyl)-1-nitrosopiperazine is 2219339-13-4.

What is the molecular formula and molecular weight of 4-(3-Chlorophenyl)-1-nitrosopiperazine?

4-(3-Chlorophenyl)-1-nitrosopiperazine has the molecular formula C10H12ClN3O and a molecular weight of 225.67 g/mol. Its IUPAC name is 1-(3-chlorophenyl)-4-nitrosopiperazine.

What is 4-(3-Chlorophenyl)-1-nitrosopiperazine used for?

4-(3-Chlorophenyl)-1-nitrosopiperazine is supplied as a characterised reference material related to Trazodone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-(3-Chlorophenyl)-1-nitrosopiperazine can I order?

We supply 4-(3-Chlorophenyl)-1-nitrosopiperazine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-(3-Chlorophenyl)-1-nitrosopiperazine?

Yes. Every lot of 4-(3-Chlorophenyl)-1-nitrosopiperazine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-(3-Chlorophenyl)-1-nitrosopiperazine be shipped internationally?

Yes. 4-(3-Chlorophenyl)-1-nitrosopiperazine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.