4-(4-Pyridinyl)thiazole-2-thiol

Name: 4-(4-Pyridinyl)thiazole-2-thiol
Brand: Vaqora Chemicals
SKU: VQ-045361

About 4-(4-Pyridinyl)thiazole-2-thiol

Vaqora Chemicals supplies 4-(4-Pyridinyl)thiazole-2-thiol, an impurity of Ceftaroline Fosamil registered under CAS number 77168-63-9. The compound has the formula C8H6N2S2, corresponding to a molecular weight of 194.3 g/mol. Systematically, it is named 4-pyridin-4-yl-3H-1,3-thiazole-2-thione. It is also known as 4-(4-pyridyl)-3H-thiazole-2-thione or 4-(4-Pyridyl)-1,3-thiazole-2-thiol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Ceftaroline Fosamil to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ceftaroline Fosamil

View every impurity, metabolite and intermediate we list for Ceftaroline Fosamil.

Ceftaroline Fosamil impurities

Specifications & identifiers

Chemical identifiers
Product name	4-(4-Pyridinyl)thiazole-2-thiol
Catalogue No.	VQ-045361
CAS Number	77168-63-9
IUPAC name	4-pyridin-4-yl-3H-1,3-thiazole-2-thione
Molecular formula	C₈H₆N₂S₂
Molecular weight	194.3 g/mol
Exact mass	193.9972
Grade	Reference Standard
HSN code	38229090
InChIKey	LEQNUYXXLYRUNY-UHFFFAOYSA-N
SMILES	C1=CN=CC=C1C2=CSC(=S)N2
PubChem CID	22392870

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	1 / 3
TPSA	82.3 Å²
Synonyms	4-(4-pyridyl)-3H-thiazole-2-thione, 4-(4-Pyridyl)-1,3-thiazole-2-thiol, 4-(4-Pyridyl)thiazole-2(3H)-thione, 4-(Pyridin-4-yl)thiazole-2(3H)-thione, 2(3H)-Thiazolethione, 4-(4-pyridinyl)-, 2(3H)-Thiazolethione, 4-(4-pyridinyl), 4-pyridin-4-yl-thiazole-2-thiol, 4-(pyridin-4-yl)-1,3-thiazole-2-thiol, 4-(Pyridin-4-yl)-1,3-thiazole-2(3H)-thione

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P261, P264, P270, P272, P273, P280, P301 + P317, P302 + P352, P321, P330, P333 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-(4-Pyridinyl)thiazole-2-thiol?

The CAS Registry Number of 4-(4-Pyridinyl)thiazole-2-thiol is 77168-63-9. It is also known as 4-(4-pyridyl)-3H-thiazole-2-thione, 4-(4-Pyridyl)-1,3-thiazole-2-thiol, 4-(4-Pyridyl)thiazole-2(3H)-thione.

What is the molecular formula and molecular weight of 4-(4-Pyridinyl)thiazole-2-thiol?

4-(4-Pyridinyl)thiazole-2-thiol has the molecular formula C8H6N2S2 and a molecular weight of 194.3 g/mol. Its IUPAC name is 4-pyridin-4-yl-3H-1,3-thiazole-2-thione.

What is 4-(4-Pyridinyl)thiazole-2-thiol used for?

4-(4-Pyridinyl)thiazole-2-thiol is supplied as a characterised reference material related to Ceftaroline Fosamil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-(4-Pyridinyl)thiazole-2-thiol can I order?

We supply 4-(4-Pyridinyl)thiazole-2-thiol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-(4-Pyridinyl)thiazole-2-thiol?

Yes. Every lot of 4-(4-Pyridinyl)thiazole-2-thiol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-(4-Pyridinyl)thiazole-2-thiol be shipped internationally?

Yes. 4-(4-Pyridinyl)thiazole-2-thiol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.