4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine

Name: 4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine
Brand: Vaqora Chemicals
SKU: VQ-029299

About 4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine

4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine (CAS 123971-45-9) is an impurity of Avatrombopag offered by Vaqora Chemicals. Its molecular formula is C7H5ClN2S2 and its molecular weight is 216.7 g/mol. Systematically, it is named 4-(5-chlorothiophen-2-yl)-1,3-thiazol-2-amine. It is also known as 2-Amino-4-(5-chlorothien-2-yl)thiazole or 4-(5-Chlorothiophen-2-yl)thiazol-2-amine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 6 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Avatrombopag, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Avatrombopag

View every impurity, metabolite and intermediate we list for Avatrombopag.

Avatrombopag impurities

Specifications & identifiers

Chemical identifiers
Product name	4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine
Catalogue No.	VQ-029299
CAS Number	123971-45-9
IUPAC name	4-(5-chlorothiophen-2-yl)-1,3-thiazol-2-amine
Molecular formula	C₇H₅ClN₂S₂
Molecular weight	216.7 g/mol
Exact mass	215.9583
Grade	Reference Standard
HSN code	38229090
InChIKey	KZOUOGWZDXYEDI-UHFFFAOYSA-N
SMILES	C1=C(SC(=C1)Cl)C2=CSC(=N2)N
PubChem CID	701782

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	1 / 4
TPSA	95.4 Å²
Synonyms	2-Amino-4-(5-chlorothien-2-yl)thiazole, 4-(5-Chlorothiophen-2-yl)thiazol-2-amine, 4-(5-Chloro-thiophen-2-yl)thiazol-2-ylamine, 2-Thiazolamine, 4-(5-chloro-2-thienyl)-, 4-(5-Chloro-2-thienyl)thiazol-2-amine, 2-Amino-4-(5-chlorothien-2-yl)-1,3-thiazole, 4-(5-chloro-2-thienyl)-1,3-thiazole-2-ylamine, 4-(5-Chlorothien-2-yl)-1,3-thiazol-2-amine, 4-(5-Chloro-2-thienyl)-2-thiazolamine, 2-Amino-4-(5-chloro-2-thienyl)thiazole, 4-(5-chloro-2-thieny)-1,3-thiazol-2-amine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine?

The CAS Registry Number of 4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine is 123971-45-9. It is also known as 2-Amino-4-(5-chlorothien-2-yl)thiazole, 4-(5-Chlorothiophen-2-yl)thiazol-2-amine, 4-(5-Chloro-thiophen-2-yl)thiazol-2-ylamine.

What is the molecular formula and molecular weight of 4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine?

4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine has the molecular formula C7H5ClN2S2 and a molecular weight of 216.7 g/mol. Its IUPAC name is 4-(5-chlorothiophen-2-yl)-1,3-thiazol-2-amine.

What is 4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine used for?

4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine is supplied as a characterised reference material related to Avatrombopag. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine can I order?

We supply 4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine?

Yes. Every lot of 4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine be shipped internationally?

Yes. 4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.