4-Acetoxybenzoic acid

Name: 4-Acetoxybenzoic acid
Brand: Vaqora Chemicals
SKU: VQ-047310

About 4-Acetoxybenzoic acid

Listed under CAS 2345-34-8, 4-Acetoxybenzoic acid is a process intermediate or related compound of Acetylsalicylic Acid available from Vaqora Chemicals. Formula C9H8O4, molecular weight 180.16 g/mol. The IUPAC name is 4-acetyloxybenzoic acid. Common synonyms include Benzoic acid, 4-(acetyloxy)- and p-Acetoxybenzoic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Acetylsalicylic Acid, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 4-Acetoxybenzoic acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Acetylsalicylic Acid

View every impurity, metabolite and intermediate we list for Acetylsalicylic Acid.

Acetylsalicylic Acid impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Acetoxybenzoic acid
Catalogue No.	VQ-047310
CAS Number	2345-34-8
IUPAC name	4-acetyloxybenzoic acid
Molecular formula	C₉H₈O₄
Molecular weight	180.16 g/mol
Exact mass	180.0423
InChIKey	GDBUZIKSJGRBJP-UHFFFAOYSA-N
SMILES	CC(=O)OC1=CC=C(C=C1)C(=O)O
PubChem CID	16865

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	1 / 4
TPSA	63.6 Å²
Synonyms	Benzoic acid, 4-(acetyloxy)-, p-Acetoxybenzoic acid, p-Acetyloxybenzoic acid, p-Carboxyphenyl acetate, Benzoic acid, p-hydroxy-, acetate, 4-(Acetyloxy)benzoic acid, 4-Carboxyphenyl acetate, p-Hydroxybenzoic acid acetate, Acetic Acid 4-Carboxyphenyl Ester

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Acetoxybenzoic acid?

The CAS Registry Number of 4-Acetoxybenzoic acid is 2345-34-8. It is also known as Benzoic acid, 4-(acetyloxy)-, p-Acetoxybenzoic acid, p-Acetyloxybenzoic acid.

What is the molecular formula and molecular weight of 4-Acetoxybenzoic acid?

4-Acetoxybenzoic acid has the molecular formula C9H8O4 and a molecular weight of 180.16 g/mol. Its IUPAC name is 4-acetyloxybenzoic acid.

What is 4-Acetoxybenzoic acid used for?

4-Acetoxybenzoic acid is supplied as a characterised reference material related to Acetylsalicylic Acid. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Acetoxybenzoic acid can I order?

We supply 4-Acetoxybenzoic acid, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Acetoxybenzoic acid?

Yes. Every lot of 4-Acetoxybenzoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Acetoxybenzoic acid be shipped internationally?

Yes. 4-Acetoxybenzoic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.