4-Amino-3-chloropyridine

Name: 4-Amino-3-chloropyridine
Brand: Vaqora Chemicals
SKU: VQ-033631

About 4-Amino-3-chloropyridine

4-Amino-3-chloropyridine (CAS 19798-77-7) is an impurity of Roflumilast offered by Vaqora Chemicals. The compound has the formula C5H5ClN2, corresponding to a molecular weight of 128.56 g/mol. Systematically, it is named 3-chloropyridin-4-amine. It is also known as 4-Pyridinamine, 3-chloro- or 3-Chloro-4-aminopyridine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 8 hazard statements. Review the Safety Data Sheet before use.

This Roflumilast impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-Amino-3-chloropyridine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Roflumilast

View every impurity, metabolite and intermediate we list for Roflumilast.

Roflumilast impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Amino-3-chloropyridine
Catalogue No.	VQ-033631
CAS Number	19798-77-7
IUPAC name	3-chloropyridin-4-amine
Molecular formula	C₅H₅ClN₂
Molecular weight	128.56 g/mol
Exact mass	128.0141
Grade	Reference Standard
HSN code	38229090
InChIKey	KJBKPRMEMJKXDV-UHFFFAOYSA-N
SMILES	C1=CN=CC(=C1N)Cl
PubChem CID	581853

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	1 / 2
TPSA	38.9 Å²
Synonyms	4-Pyridinamine, 3-chloro-, 3-Chloro-4-aminopyridine, 3-Chloro-4-pyridinamine, 3-Chloro-pyridin-4-ylamine, 3-Chloropyrid-4-ylamine, 3-chloro-4-pyridinylamine, 3-chloranylpyridin-4-amine, Pyridine, 4-amino-3-chloro-, 4-amino-3-chloropyridine, AldrichCPR, 3-chloro-4-pyridylamine, (3-chloro-4-pyridyl)amine

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Amino-3-chloropyridine?

The CAS Registry Number of 4-Amino-3-chloropyridine is 19798-77-7. It is also known as 4-Pyridinamine, 3-chloro-, 3-Chloro-4-aminopyridine, 3-Chloro-4-pyridinamine.

What is the molecular formula and molecular weight of 4-Amino-3-chloropyridine?

4-Amino-3-chloropyridine has the molecular formula C5H5ClN2 and a molecular weight of 128.56 g/mol. Its IUPAC name is 3-chloropyridin-4-amine.

What is 4-Amino-3-chloropyridine used for?

4-Amino-3-chloropyridine is supplied as a characterised reference material related to Roflumilast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Amino-3-chloropyridine can I order?

We supply 4-Amino-3-chloropyridine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Amino-3-chloropyridine?

Yes. Every lot of 4-Amino-3-chloropyridine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Amino-3-chloropyridine be shipped internationally?

Yes. 4-Amino-3-chloropyridine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.