4-Chloro-1,3-phenylenediamine

Name: 4-Chloro-1,3-phenylenediamine
Brand: Vaqora Chemicals
SKU: VQ-049541

About 4-Chloro-1,3-phenylenediamine

Listed under CAS 5131-60-2, 4-Chloro-1,3-phenylenediamine is a process intermediate or related compound of Bendamustine available from Vaqora Chemicals. Its molecular formula is C6H7ClN2 and its molecular weight is 142.58 g/mol. Systematically, it is named 4-chlorobenzene-1,3-diamine. Common synonyms include 4-Chloro-1,3-benzenediamine and 4-Chloro-1,3-diaminobenzene.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Bendamustine, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-Chloro-1,3-phenylenediamine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Bendamustine

View every impurity, metabolite and intermediate we list for Bendamustine.

Bendamustine impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Chloro-1,3-phenylenediamine
Catalogue No.	VQ-049541
CAS Number	5131-60-2
IUPAC name	4-chlorobenzene-1,3-diamine
Molecular formula	C₆H₇ClN₂
Molecular weight	142.58 g/mol
Exact mass	142.0298
HSN code	2933
InChIKey	ZWUBBMDHSZDNTA-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1N)N)Cl
PubChem CID	21209

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	2 / 2
TPSA	52 Å²
Synonyms	4-Chloro-1,3-benzenediamine, 4-Chloro-1,3-diaminobenzene, 1-Chloro-2,4-diaminobenzene, 4-Chloro-meta-phenylenediamine, m-Phenylenediamine, 4-chloro-, 4-Chlorophene-1,3-diamine, 4-Chloro-3-phenylenediamine, 4-Chlorophenylene-1,3-diamine, 4-Cl-m-PD, 1,3-Benzenediamine, 4-chloro-, p-Chlor-m-fenylendiamin

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Chloro-1,3-phenylenediamine?

The CAS Registry Number of 4-Chloro-1,3-phenylenediamine is 5131-60-2. It is also known as 4-Chloro-1,3-benzenediamine, 4-Chloro-1,3-diaminobenzene, 1-Chloro-2,4-diaminobenzene.

What is the molecular formula and molecular weight of 4-Chloro-1,3-phenylenediamine?

4-Chloro-1,3-phenylenediamine has the molecular formula C6H7ClN2 and a molecular weight of 142.58 g/mol. Its IUPAC name is 4-chlorobenzene-1,3-diamine.

What is 4-Chloro-1,3-phenylenediamine used for?

4-Chloro-1,3-phenylenediamine is supplied as a characterised reference material related to Bendamustine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Chloro-1,3-phenylenediamine can I order?

We supply 4-Chloro-1,3-phenylenediamine, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Chloro-1,3-phenylenediamine?

Yes. Every lot of 4-Chloro-1,3-phenylenediamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Chloro-1,3-phenylenediamine be shipped internationally?

Yes. 4-Chloro-1,3-phenylenediamine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.