4-Chlorobenzotrichloride

Name: 4-Chlorobenzotrichloride
Brand: Vaqora Chemicals
SKU: VQ-023388

About 4-Chlorobenzotrichloride

Listed under CAS 5216-25-1, 4-Chlorobenzotrichloride is an impurity of Fluoxetine available from Vaqora Chemicals. Formula C7H4Cl4, molecular weight 229.9 g/mol. Its systematic (IUPAC) name is 1-chloro-4-(trichloromethyl)benzene. Common synonyms include Benzene, 1-chloro-4-(trichloromethyl)- and p-Chlorophenyltrichloromethane.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Fluoxetine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Fluoxetine

View every impurity, metabolite and intermediate we list for Fluoxetine.

Fluoxetine impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Chlorobenzotrichloride
Catalogue No.	VQ-023388
CAS Number	5216-25-1
IUPAC name	1-chloro-4-(trichloromethyl)benzene
Molecular formula	C₇H₄Cl₄
Molecular weight	229.9 g/mol
Exact mass	229.9038
Grade	Reference Standard
HSN code	38229090
InChIKey	LVZPKYYPPLUECL-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C(Cl)(Cl)Cl)Cl
PubChem CID	21277

Physical properties
Physical form	Solid
LogP (XLogP3)	4.6
H-bond donors / acceptors	0 / 0
TPSA	0 Å²
Synonyms	Benzene, 1-chloro-4-(trichloromethyl)-, p-Chlorophenyltrichloromethane, alpha,alpha,alpha-Trichloro-4-chlorotoluene, p,alpha,alpha,alpha-Tetrachlorotoluene, Toluene, p,alpha,alpha,alpha-tetrachloro-, 4,alpha,alpha,alpha-Tetrachlorotoluene, p-Chlorobenzotrichloride, alpha,alpha,alpha,4-Tetrachlorotoluene, p-Trichloromethylchlorobenzene, Toluene, p,.alpha.,.alpha.,.alpha.-tetrachloro-, 4,.alpha.,.alpha.,.alpha.-Tetrachlorotoluene, .alpha.,.alpha.,.alpha.-Trichloro-4-chlorotoluene

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H335May cause respiratory irritation
H350May cause cancer

Precautionary statements: P203, P260, P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P318, P319, P321, P330, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Chlorobenzotrichloride?

The CAS Registry Number of 4-Chlorobenzotrichloride is 5216-25-1. It is also known as Benzene, 1-chloro-4-(trichloromethyl)-, p-Chlorophenyltrichloromethane, alpha,alpha,alpha-Trichloro-4-chlorotoluene.

What is the molecular formula and molecular weight of 4-Chlorobenzotrichloride?

4-Chlorobenzotrichloride has the molecular formula C7H4Cl4 and a molecular weight of 229.9 g/mol. Its IUPAC name is 1-chloro-4-(trichloromethyl)benzene.

What is 4-Chlorobenzotrichloride used for?

4-Chlorobenzotrichloride is supplied as a characterised reference material related to Fluoxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Chlorobenzotrichloride can I order?

We supply 4-Chlorobenzotrichloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Chlorobenzotrichloride?

Yes. Every lot of 4-Chlorobenzotrichloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Chlorobenzotrichloride be shipped internationally?

Yes. 4-Chlorobenzotrichloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.