4-(Difluoromethoxy)-1,2-benzenediamine

Name: 4-(Difluoromethoxy)-1,2-benzenediamine
Brand: Vaqora Chemicals
SKU: VQ-013067

About 4-(Difluoromethoxy)-1,2-benzenediamine

4-(Difluoromethoxy)-1,2-benzenediamine (CAS 172282-50-7) is a process intermediate or related compound of Pantoprazole offered by Vaqora Chemicals. Formula C7H8F2N2O, molecular weight 174.15 g/mol. The IUPAC name is 4-(difluoromethoxy)benzene-1,2-diamine. It is also known as 1,2-Diamino-4-difluoromethoxy Benzene or 2-Amino-4-difluoromethoxyaniline.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 6 hazard statements. Review the Safety Data Sheet before use.

Process chemists and analysts use it when developing synthetic routes to Pantoprazole, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Pantoprazole

View every impurity, metabolite and intermediate we list for Pantoprazole.

Pantoprazole impurities

Specifications & identifiers

Chemical identifiers
Product name	4-(Difluoromethoxy)-1,2-benzenediamine
Catalogue No.	VQ-013067
CAS Number	172282-50-7
IUPAC name	4-(difluoromethoxy)benzene-1,2-diamine
Molecular formula	C₇H₈F₂N₂O
Molecular weight	174.15 g/mol
Exact mass	174.0605
Grade	Reference Standard
HSN code	2933
InChIKey	GRBDLKBKKHPPQX-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1OC(F)F)N)N
PubChem CID	15158201

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	2 / 5
TPSA	61.3 Å²
Synonyms	1,2-Diamino-4-difluoromethoxy Benzene, 2-Amino-4-difluoromethoxyaniline, 4-Difluoromethoxybenzene-1,2-diamine, 4-(Difluoromethoxy)-1,2-benzenediamine, 4-Difluoromethoxy-1,2-phenylendiamine, 1,2-Benzenediamine, 4-(difluoromethoxy)-, 1,2-Diamino-4-(difluoromethoxy)benzene, Pantoprazole sodium F-4, 4-difluormethoxy-benzene-1,2-diamine, 4-Difluoromethoxy-1,2-benzenediamine, 4-difluoromethoxy-benzene-1,2-diamine

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H318Causes serious eye damage
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-(Difluoromethoxy)-1,2-benzenediamine?

The CAS Registry Number of 4-(Difluoromethoxy)-1,2-benzenediamine is 172282-50-7. It is also known as 1,2-Diamino-4-difluoromethoxy Benzene, 2-Amino-4-difluoromethoxyaniline, 4-Difluoromethoxybenzene-1,2-diamine.

What is the molecular formula and molecular weight of 4-(Difluoromethoxy)-1,2-benzenediamine?

4-(Difluoromethoxy)-1,2-benzenediamine has the molecular formula C7H8F2N2O and a molecular weight of 174.15 g/mol. Its IUPAC name is 4-(difluoromethoxy)benzene-1,2-diamine.

What is 4-(Difluoromethoxy)-1,2-benzenediamine used for?

4-(Difluoromethoxy)-1,2-benzenediamine is supplied as a characterised reference material related to Pantoprazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-(Difluoromethoxy)-1,2-benzenediamine can I order?

We supply 4-(Difluoromethoxy)-1,2-benzenediamine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-(Difluoromethoxy)-1,2-benzenediamine?

Yes. Every lot of 4-(Difluoromethoxy)-1,2-benzenediamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-(Difluoromethoxy)-1,2-benzenediamine be shipped internationally?

Yes. 4-(Difluoromethoxy)-1,2-benzenediamine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.