4-Hydroxy Atorvastatin Lactone

Name: 4-Hydroxy Atorvastatin Lactone
Brand: Vaqora Chemicals
SKU: VQ-021657

About 4-Hydroxy Atorvastatin Lactone

4-Hydroxy Atorvastatin Lactone (CAS 163217-70-7) is a metabolite or degradation product of Atorvastatin offered by Vaqora Chemicals. Its molecular formula is C33H33FN2O5 and its molecular weight is 556.6 g/mol. Common synonyms include Atorvastatin 4-Hydroxy Lactone and para-Hydroxy Atorvastatin Lactone.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Atorvastatin, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Atorvastatin

View every impurity, metabolite and intermediate we list for Atorvastatin.

Atorvastatin impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Hydroxy Atorvastatin Lactone
Catalogue No.	VQ-021657
CAS Number	163217-70-7
IUPAC name	5-(4-fluorophenyl)-1-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-N-(4-hydroxyphenyl)-4-phenyl-2-propan-2-ylpyrrole-3-carboxamide
Molecular formula	C₃₃H₃₃FN₂O₅
Molecular weight	556.6 g/mol
Exact mass	556.2374
Grade	Reference Standard
HSN code	38229090
InChIKey	KDJMDZSAAFACAM-KAYWLYCHSA-N
SMILES	CC(C)C1=C(C(=C(N1CC[C@@H]2C[C@H](CC(=O)O2)O)C3=CC=C(C=C3)F)C4=CC=CC=C4)C(=O)NC5=CC=C(C=C5)O
PubChem CID	9937602

Physical properties
Physical form	Solid
LogP (XLogP3)	5.4
H-bond donors / acceptors	3 / 6
TPSA	101 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Hydroxy Atorvastatin Lactone?

The CAS Registry Number of 4-Hydroxy Atorvastatin Lactone is 163217-70-7. It is also known as Atorvastatin 4-Hydroxy Lactone, para-Hydroxy Atorvastatin Lactone, p-Hydroxy atorvastatin lactone.

What is the molecular formula and molecular weight of 4-Hydroxy Atorvastatin Lactone?

4-Hydroxy Atorvastatin Lactone has the molecular formula C33H33FN2O5 and a molecular weight of 556.6 g/mol. Its IUPAC name is 5-(4-fluorophenyl)-1-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-N-(4-hydroxyphenyl)-4-phenyl-2-propan-2-ylpyrrole-3-carboxamide.

What is 4-Hydroxy Atorvastatin Lactone used for?

4-Hydroxy Atorvastatin Lactone is supplied as a characterised reference material related to Atorvastatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Hydroxy Atorvastatin Lactone can I order?

We supply 4-Hydroxy Atorvastatin Lactone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Hydroxy Atorvastatin Lactone?

Yes. Every lot of 4-Hydroxy Atorvastatin Lactone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Hydroxy Atorvastatin Lactone be shipped internationally?

Yes. We export 4-Hydroxy Atorvastatin Lactone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.