4-Hydroxy Nebivolol

Name: 4-Hydroxy Nebivolol
Brand: Vaqora Chemicals
SKU: VQ-032076

About 4-Hydroxy Nebivolol

4-Hydroxy Nebivolol (CAS 178383-76-1) is a metabolite or degradation product of Nebivolol offered by Vaqora Chemicals. With the molecular formula C22H28ClF2NO6, it has a molar mass of 475.9 g/mol. It is also known as 4-Hydroxy Nebivolol HCl or 4-Hydroxy Nebivolol, Hydrochloride Hydrate.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Nebivolol, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4-Hydroxy Nebivolol is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Nebivolol

View every impurity, metabolite and intermediate we list for Nebivolol.

Nebivolol impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Hydroxy Nebivolol
Catalogue No.	VQ-032076
CAS Number	178383-76-1
IUPAC name	6-fluoro-2-[2-[[2-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]-1-hydroxyethyl]-3,4-dihydro-2H-chromen-4-ol;hydrate;hydrochloride
Molecular formula	C₂₂H₂₈ClF₂NO₆
Molecular weight	475.9 g/mol
Exact mass	475.1573
Grade	Reference Standard
HSN code	38229090
InChIKey	NNLYRGGZJNHZRC-UHFFFAOYSA-N
SMILES	C1CC2=C(C=CC(=C2)F)OC1C(CNCC(C3CC(C4=C(O3)C=CC(=C4)F)O)O)O.O.Cl
PubChem CID	71433852

Physical properties
Physical form	Solid
H-bond donors / acceptors	6 / 9
TPSA	92.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Hydroxy Nebivolol?

The CAS Registry Number of 4-Hydroxy Nebivolol is 178383-76-1. It is also known as 4-Hydroxy Nebivolol HCl, 4-Hydroxy Nebivolol, Hydrochloride Hydrate.

What is the molecular formula and molecular weight of 4-Hydroxy Nebivolol?

4-Hydroxy Nebivolol has the molecular formula C22H28ClF2NO6 and a molecular weight of 475.9 g/mol.

What is 4-Hydroxy Nebivolol used for?

4-Hydroxy Nebivolol is supplied as a characterised reference material related to Nebivolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Hydroxy Nebivolol can I order?

We supply 4-Hydroxy Nebivolol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Hydroxy Nebivolol?

Yes. Every lot of 4-Hydroxy Nebivolol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Hydroxy Nebivolol be shipped internationally?

Yes. We export 4-Hydroxy Nebivolol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.