4-Hydroxybenzenesulfonamide

Name: 4-Hydroxybenzenesulfonamide
Brand: Vaqora Chemicals
SKU: VQ-029723

About 4-Hydroxybenzenesulfonamide

4-Hydroxybenzenesulfonamide is a metabolite or degradation product of Celecoxib carrying the CAS registry number 1576-43-8. Formula C6H7NO3S, molecular weight 173.19 g/mol. Common synonyms include Benzenesulfonamide, 4-hydroxy- and p-Hydroxybenzenesulfonamide.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Celecoxib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4-Hydroxybenzenesulfonamide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Celecoxib

View every impurity, metabolite and intermediate we list for Celecoxib.

Celecoxib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Hydroxybenzenesulfonamide
Catalogue No.	VQ-029723
CAS Number	1576-43-8
IUPAC name	4-hydroxybenzenesulfonamide
Molecular formula	C₆H₇NO₃S
Molecular weight	173.19 g/mol
Exact mass	173.0147
Grade	Reference Standard
HSN code	38229090
InChIKey	DIRCLGLKRZLKHG-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1O)S(=O)(=O)N
PubChem CID	74093

Physical properties
Physical form	Solid
LogP (XLogP3)	0.1
H-bond donors / acceptors	2 / 4
TPSA	88.8 Å²
Synonyms	Benzenesulfonamide, 4-hydroxy-, p-Hydroxybenzenesulfonamide, p-Phenolsulfonamide, 4-Sulfamoylphenol, Benzenesulfonamide, p-hydroxy-, p-Sulfamidophenol, p-Hydroxybenzenesulphonamide, 4-hydroxybenzenesulphonamide, 4-hydroxybenzene-1-sulfonamide, 4-Hydroxyphenylsulfonamide, 4-oxidanylbenzenesulfonamide, p-Hydroxy-benzene derivative, 3a

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Hydroxybenzenesulfonamide?

The CAS Registry Number of 4-Hydroxybenzenesulfonamide is 1576-43-8. It is also known as Benzenesulfonamide, 4-hydroxy-, p-Hydroxybenzenesulfonamide, p-Phenolsulfonamide.

What is the molecular formula and molecular weight of 4-Hydroxybenzenesulfonamide?

4-Hydroxybenzenesulfonamide has the molecular formula C6H7NO3S and a molecular weight of 173.19 g/mol. Its IUPAC name is 4-hydroxybenzenesulfonamide.

What is 4-Hydroxybenzenesulfonamide used for?

4-Hydroxybenzenesulfonamide is supplied as a characterised reference material related to Celecoxib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Hydroxybenzenesulfonamide can I order?

We supply 4-Hydroxybenzenesulfonamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Hydroxybenzenesulfonamide?

Yes. Every lot of 4-Hydroxybenzenesulfonamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Hydroxybenzenesulfonamide be shipped internationally?

Yes. 4-Hydroxybenzenesulfonamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.