4-Hydroxybenzotrifluoride

Name: 4-Hydroxybenzotrifluoride
Brand: Vaqora Chemicals
SKU: VQ-013112

About 4-Hydroxybenzotrifluoride

Vaqora Chemicals supplies 4-Hydroxybenzotrifluoride, a process intermediate or related compound of Fluoxetine registered under CAS number 402-45-9. Its molecular formula is C7H5F3O and its molecular weight is 162.11 g/mol. The IUPAC name is 4-(trifluoromethyl)phenol. It is also known as p-Trifluoromethylphenol or alpha,alpha,alpha-Trifluoro-4-cresol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Fluoxetine, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 5 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Fluoxetine

View every impurity, metabolite and intermediate we list for Fluoxetine.

Fluoxetine impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Hydroxybenzotrifluoride
Catalogue No.	VQ-013112
CAS Number	402-45-9
IUPAC name	4-(trifluoromethyl)phenol
Molecular formula	C₇H₅F₃O
Molecular weight	162.11 g/mol
Exact mass	162.0292
Grade	Reference Standard
InChIKey	BAYGVMXZJBFEMB-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C(F)(F)F)O
PubChem CID	67874

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	1 / 4
TPSA	20.2 Å²
Synonyms	p-Trifluoromethylphenol, alpha,alpha,alpha-Trifluoro-4-cresol, 4-Trifluoromethylphenol, alpha,alpha,alpha-Trifluoro-p-cresol, TFMP cpd, p-Hydroxybenzotrifluoride, Phenol, 4-(trifluoromethyl)-, 4-(Trifluoromethyl)-phenol, para-trifluoromethylphenol, .alpha.,.alpha.,.alpha.-Trifluoro-p-cresol, a,a,a-Trifluoro-p-cresol, 4-trifluoromethyl-phenol

Safety & hazard information (GHS)

Flammable

Corrosive

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H228Flammable solid
H301Toxic if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation

Precautionary statements: P210, P240, P241, P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P362 + P364, P370 + P378, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Hydroxybenzotrifluoride?

The CAS Registry Number of 4-Hydroxybenzotrifluoride is 402-45-9. It is also known as p-Trifluoromethylphenol, alpha,alpha,alpha-Trifluoro-4-cresol, 4-Trifluoromethylphenol.

What is the molecular formula and molecular weight of 4-Hydroxybenzotrifluoride?

4-Hydroxybenzotrifluoride has the molecular formula C7H5F3O and a molecular weight of 162.11 g/mol. Its IUPAC name is 4-(trifluoromethyl)phenol.

What is 4-Hydroxybenzotrifluoride used for?

4-Hydroxybenzotrifluoride is supplied as a characterised reference material related to Fluoxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Hydroxybenzotrifluoride can I order?

We supply 4-Hydroxybenzotrifluoride in Reference Standard grade, in 5 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Hydroxybenzotrifluoride?

Yes. Every lot of 4-Hydroxybenzotrifluoride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Hydroxybenzotrifluoride be shipped internationally?

Yes. 4-Hydroxybenzotrifluoride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.