4-Hydroxyphenyl Carvedilol

Name: 4-Hydroxyphenyl Carvedilol
Brand: Vaqora Chemicals
SKU: VQ-021078

About 4-Hydroxyphenyl Carvedilol

4-Hydroxyphenyl Carvedilol is a metabolite or degradation product of Carvedilol carrying the CAS registry number 142227-49-4. With the molecular formula C24H26N2O5, it has a molar mass of 422.5 g/mol. Its systematic (IUPAC) name is 4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxyphenol. Common synonyms include Carvedilol 4-Hydroxy Metabolite and 4-Hydroxycarvedilol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Analytical teams use this compound to identify metabolites and degradants of Carvedilol, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-Hydroxyphenyl Carvedilol in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Carvedilol

View every impurity, metabolite and intermediate we list for Carvedilol.

Carvedilol impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Hydroxyphenyl Carvedilol
Catalogue No.	VQ-021078
CAS Number	142227-49-4
IUPAC name	4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxyphenol
Molecular formula	C₂₄H₂₆N₂O₅
Molecular weight	422.5 g/mol
Exact mass	422.1842
Grade	Reference Standard
HSN code	38229090
InChIKey	ZCJHEORDHXCJNB-UHFFFAOYSA-N
SMILES	COC1=C(C=CC(=C1)O)OCCNCC(COC2=CC=CC3=C2C4=CC=CC=C4N3)O
PubChem CID	4572774

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	4 / 6
TPSA	96 Å²
Synonyms	Carvedilol 4-Hydroxy Metabolite, 4-(2-{[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino}ethoxy)-3-methoxyphenol, 4-(2-((3-(9H-Carbazol-4-yloxy)-2-hydroxypropyl)amino)ethoxy)-3-methoxyphenol, 4-Hydroxycarvedilol, 4'-Hydroxycarvedilol, Carvedilol metabolite 4-Hydroxyphenyl Carvedilol, Phenol, 4-(2-((3-(9H-carbazol-4-yloxy)-2-hydroxypropyl)amino)ethoxy)-3-methoxy-, Phenol, 4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxy-

Safety & hazard information (GHS)

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H373May causes damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P260, P273, P319, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Hydroxyphenyl Carvedilol?

The CAS Registry Number of 4-Hydroxyphenyl Carvedilol is 142227-49-4. It is also known as Carvedilol 4-Hydroxy Metabolite, 4-(2-{[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino}ethoxy)-3-methoxyphenol, 4-(2-((3-(9H-Carbazol-4-yloxy)-2-hydroxypropyl)amino)ethoxy)-3-methoxyphenol.

What is the molecular formula and molecular weight of 4-Hydroxyphenyl Carvedilol?

4-Hydroxyphenyl Carvedilol has the molecular formula C24H26N2O5 and a molecular weight of 422.5 g/mol. Its IUPAC name is 4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxyphenol.

What is 4-Hydroxyphenyl Carvedilol used for?

4-Hydroxyphenyl Carvedilol is supplied as a characterised reference material related to Carvedilol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Hydroxyphenyl Carvedilol can I order?

We supply 4-Hydroxyphenyl Carvedilol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Hydroxyphenyl Carvedilol?

Yes. Every lot of 4-Hydroxyphenyl Carvedilol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Hydroxyphenyl Carvedilol be shipped internationally?

Yes. 4-Hydroxyphenyl Carvedilol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.