4-Hydroxyphenytoin

Name: 4-Hydroxyphenytoin
Brand: Vaqora Chemicals
SKU: VQ-041455

About 4-Hydroxyphenytoin

4-Hydroxyphenytoin (CAS 2784-27-2) is a metabolite or degradation product of Phenytoin offered by Vaqora Chemicals. With the molecular formula C15H12N2O3, it has a molar mass of 268.27 g/mol. Its systematic (IUPAC) name is 5-(4-hydroxyphenyl)-5-phenylimidazolidine-2,4-dione. Common synonyms include 5-(4-Hydroxyphenyl)-5-phenylhydantoin and Hydroxyphenytoin.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Phenytoin, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Phenytoin

View every impurity, metabolite and intermediate we list for Phenytoin.

Phenytoin impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Hydroxyphenytoin
Catalogue No.	VQ-041455
CAS Number	2784-27-2
IUPAC name	5-(4-hydroxyphenyl)-5-phenylimidazolidine-2,4-dione
Molecular formula	C₁₅H₁₂N₂O₃
Molecular weight	268.27 g/mol
Exact mass	268.0848
Grade	Reference Standard
HSN code	38229090
InChIKey	XEEDURHPFVXALT-UHFFFAOYSA-N
SMILES	C1=CC=C(C=C1)C2(C(=O)NC(=O)N2)C3=CC=C(C=C3)O
PubChem CID	17732

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	3 / 3
TPSA	78.4 Å²
Synonyms	5-(4-Hydroxyphenyl)-5-phenylhydantoin, Hydroxyphenytoin, p-Hydroxyphenytoin, 4-Hydroxydiphenylhydantoin, 5-(p-Hydroxyphenyl)-5-phenylhydantoin, p-Hydroxydiphenylhydantoin, (p-Hydroxyphenyl)phenylhydantoin, (Hydroxyphenyl)phenylhydantoin, para-Hydroxyphenytoin, 5-(4'-Hydroxyphenyl)-5-phenylhydantoin, 5-(4-Hydroxyphenyl)-5-phenyl-2,4-imidazolidinedione, 2,4-Imidazolidinedione, 5-(4-hydroxyphenyl)-5-phenyl-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Hydroxyphenytoin?

The CAS Registry Number of 4-Hydroxyphenytoin is 2784-27-2. It is also known as 5-(4-Hydroxyphenyl)-5-phenylhydantoin, Hydroxyphenytoin, p-Hydroxyphenytoin.

What is the molecular formula and molecular weight of 4-Hydroxyphenytoin?

4-Hydroxyphenytoin has the molecular formula C15H12N2O3 and a molecular weight of 268.27 g/mol. Its IUPAC name is 5-(4-hydroxyphenyl)-5-phenylimidazolidine-2,4-dione.

What is 4-Hydroxyphenytoin used for?

4-Hydroxyphenytoin is supplied as a characterised reference material related to Phenytoin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Hydroxyphenytoin can I order?

We supply 4-Hydroxyphenytoin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Hydroxyphenytoin?

Yes. Every lot of 4-Hydroxyphenytoin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Hydroxyphenytoin be shipped internationally?

Yes. 4-Hydroxyphenytoin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.