4-Methoxybenzyl Chloride

Name: 4-Methoxybenzyl Chloride
Brand: Vaqora Chemicals
SKU: VQ-049676

About 4-Methoxybenzyl Chloride

4-Methoxybenzyl Chloride (CAS 824-94-2) is a process intermediate or related compound of Venlafaxine offered by Vaqora Chemicals. The compound has the formula C8H9ClO, corresponding to a molecular weight of 156.61 g/mol. Its systematic (IUPAC) name is 1-(chloromethyl)-4-methoxybenzene. Common synonyms include p-Methoxybenzyl chloride and p-Anisyl chloride.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 1 hazard statement. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Venlafaxine, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 4-Methoxybenzyl Chloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Venlafaxine

View every impurity, metabolite and intermediate we list for Venlafaxine.

Venlafaxine impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Methoxybenzyl Chloride
Catalogue No.	VQ-049676
CAS Number	824-94-2
IUPAC name	1-(chloromethyl)-4-methoxybenzene
Molecular formula	C₈H₉ClO
Molecular weight	156.61 g/mol
Exact mass	156.0342
InChIKey	MOHYOXXOKFQHDC-UHFFFAOYSA-N
SMILES	COC1=CC=C(C=C1)CCl
PubChem CID	69993

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	0 / 1
TPSA	9.2 Å²
Synonyms	p-Methoxybenzyl chloride, p-Anisyl chloride, 4-(Chloromethyl)anisole, p-(Chloromethyl)anisole, Benzene, 1-(chloromethyl)-4-methoxy-, alpha-Chloro-4-methoxytoluene, Anisole, p-(chloromethyl)-, 4-Methyloxybenzyl chloride, .alpha.-Chloro-4-methoxytoluene, 4-(chloromethyl)-1-methoxybenzene, 4-(chloromethyl)phenyl methyl ether, 1-(chloromethyl)-4-(methyloxy)benzene

Safety & hazard information (GHS)

Corrosive

Signal word: Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements: P260, P264, P280, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P321, P363, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Methoxybenzyl Chloride?

The CAS Registry Number of 4-Methoxybenzyl Chloride is 824-94-2. It is also known as p-Methoxybenzyl chloride, p-Anisyl chloride, 4-(Chloromethyl)anisole.

What is the molecular formula and molecular weight of 4-Methoxybenzyl Chloride?

4-Methoxybenzyl Chloride has the molecular formula C8H9ClO and a molecular weight of 156.61 g/mol. Its IUPAC name is 1-(chloromethyl)-4-methoxybenzene.

What is 4-Methoxybenzyl Chloride used for?

4-Methoxybenzyl Chloride is supplied as a characterised reference material related to Venlafaxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Methoxybenzyl Chloride can I order?

We supply 4-Methoxybenzyl Chloride, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Methoxybenzyl Chloride?

Yes. Every lot of 4-Methoxybenzyl Chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Methoxybenzyl Chloride be shipped internationally?

Yes. 4-Methoxybenzyl Chloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.