4-Methylphthalic anhydride

Name: 4-Methylphthalic anhydride
Brand: Vaqora Chemicals
SKU: VQ-039716

About 4-Methylphthalic anhydride

Vaqora Chemicals supplies 4-Methylphthalic anhydride, an API impurity reference standard registered under CAS number 19438-61-0. Its molecular formula is C9H6O3 and its molecular weight is 162.14 g/mol. Its systematic (IUPAC) name is 5-methyl-2-benzofuran-1,3-dione. Common synonyms include 1,3-Isobenzofurandione, 5-methyl- and Phthalic anhydride, 4-methyl-.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of the parent drug substance to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Specifications & identifiers

Chemical identifiers
Product name	4-Methylphthalic anhydride
Catalogue No.	VQ-039716
CAS Number	19438-61-0
IUPAC name	5-methyl-2-benzofuran-1,3-dione
Molecular formula	C₉H₆O₃
Molecular weight	162.14 g/mol
Exact mass	162.0317
Grade	Reference Standard
HSN code	38229090
InChIKey	ZOXBWJMCXHTKNU-UHFFFAOYSA-N
SMILES	CC1=CC2=C(C=C1)C(=O)OC2=O
PubChem CID	88069

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	0 / 3
TPSA	43.4 Å²
Synonyms	1,3-Isobenzofurandione, 5-methyl-, Phthalic anhydride, 4-methyl-, 4-methylphthalic acid anhydride, Phthalic anhydride, 4methyl, 5Methylisobenzofuran1,3dione, 4Methylphthalic acid anhydride, 1,3Isobenzofurandione, 5methyl, 5-methyl-1,3-dihydro-2-benzofuran-1,3-dione, 4-Methylphthalic anhydryde

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Methylphthalic anhydride?

The CAS Registry Number of 4-Methylphthalic anhydride is 19438-61-0. It is also known as 1,3-Isobenzofurandione, 5-methyl-, Phthalic anhydride, 4-methyl-, 4-methylphthalic acid anhydride.

What is the molecular formula and molecular weight of 4-Methylphthalic anhydride?

4-Methylphthalic anhydride has the molecular formula C9H6O3 and a molecular weight of 162.14 g/mol. Its IUPAC name is 5-methyl-2-benzofuran-1,3-dione.

Which grade and pack sizes of 4-Methylphthalic anhydride can I order?

We supply 4-Methylphthalic anhydride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Methylphthalic anhydride?

Yes. Every lot of 4-Methylphthalic anhydride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Methylphthalic anhydride be shipped internationally?

Yes. 4-Methylphthalic anhydride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.