4-Nitroguaiacol

Name: 4-Nitroguaiacol
Brand: Vaqora Chemicals
SKU: VQ-039118

About 4-Nitroguaiacol

4-Nitroguaiacol is an impurity of Bosutinib carrying the CAS registry number 3251-56-7. Its molecular formula is C7H7NO4 and its molecular weight is 169.13 g/mol. Systematically, it is named 2-methoxy-4-nitrophenol. Common synonyms include Phenol, 2-methoxy-4-nitro- and Phenol, o-methoxy-p-nitro-.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Bosutinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-Nitroguaiacol in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Bosutinib

View every impurity, metabolite and intermediate we list for Bosutinib.

Bosutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Nitroguaiacol
Catalogue No.	VQ-039118
CAS Number	3251-56-7
IUPAC name	2-methoxy-4-nitrophenol
Molecular formula	C₇H₇NO₄
Molecular weight	169.13 g/mol
Exact mass	169.0375
Grade	Reference Standard
HSN code	38229090
InChIKey	IZLVFLOBTPURLP-UHFFFAOYSA-N
SMILES	COC1=C(C=CC(=C1)[N+](=O)[O-])O
PubChem CID	76738

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	1 / 4
TPSA	75.3 Å²
Synonyms	Phenol, 2-methoxy-4-nitro-, Phenol, o-methoxy-p-nitro-, o-Methoxy-p-nitrophenol, 4-nitro-2-methoxyphenol, Mononitro guaiacol, 3-Nitro-6-hydroxyanisole, Guaiacol, 4-nitro-, 4-Hydroxy-3-methoxynitrobenzene, 2-methoxy-4-nitro-phenol, 2-hydroxy-5-nitroanisole, 2-(Methyloxy)-4-nitrophenol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Nitroguaiacol?

The CAS Registry Number of 4-Nitroguaiacol is 3251-56-7. It is also known as Phenol, 2-methoxy-4-nitro-, Phenol, o-methoxy-p-nitro-, o-Methoxy-p-nitrophenol.

What is the molecular formula and molecular weight of 4-Nitroguaiacol?

4-Nitroguaiacol has the molecular formula C7H7NO4 and a molecular weight of 169.13 g/mol. Its IUPAC name is 2-methoxy-4-nitrophenol.

What is 4-Nitroguaiacol used for?

4-Nitroguaiacol is supplied as a characterised reference material related to Bosutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Nitroguaiacol can I order?

We supply 4-Nitroguaiacol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Nitroguaiacol?

Yes. Every lot of 4-Nitroguaiacol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Nitroguaiacol be shipped internationally?

Yes. 4-Nitroguaiacol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.