4-Nitrosodiphenylamine

Name: 4-Nitrosodiphenylamine
Brand: Vaqora Chemicals
SKU: VQ-041094

About 4-Nitrosodiphenylamine

Vaqora Chemicals supplies 4-Nitrosodiphenylamine, a nitrosamine impurity of Nitroso registered under CAS number 156-10-5. The compound has the formula C12H10N2O, corresponding to a molecular weight of 198.22 g/mol. Systematically, it is named 4-nitroso-N-phenylaniline. Alternative names: p-Nitrosodiphenylamine and Naugard TKB.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Nitroso

View every impurity, metabolite and intermediate we list for Nitroso.

Nitroso impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Nitrosodiphenylamine
Catalogue No.	VQ-041094
CAS Number	156-10-5
IUPAC name	4-nitroso-N-phenylaniline
Molecular formula	C₁₂H₁₀N₂O
Molecular weight	198.22 g/mol
Exact mass	198.0793
Grade	Reference Standard
HSN code	38229090
InChIKey	OIJHFHYPXWSVPF-UHFFFAOYSA-N
SMILES	C1=CC=C(C=C1)NC2=CC=C(C=C2)N=O
PubChem CID	9074

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	1 / 3
TPSA	41.5 Å²
Synonyms	p-Nitrosodiphenylamine, Naugard TKB, N-Phenyl-p-nitrosoaniline, Diphenylamine, 4-nitroso-, p-Nitrosodifenylamin, 4-Nitroso-N-phenylbenzenamine, p-Nitroso-N-phenylaniline, p-Phenylaminonitrosobenzene, Nitrous diphenylamide, N-Phenyl-para-nitrosoaniline, para-Nitroso-N-phenylaniline, Amine, diphenyl, 4-nitroso-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Nitrosodiphenylamine?

The CAS Registry Number of 4-Nitrosodiphenylamine is 156-10-5. It is also known as p-Nitrosodiphenylamine, Naugard TKB, N-Phenyl-p-nitrosoaniline.

What is the molecular formula and molecular weight of 4-Nitrosodiphenylamine?

4-Nitrosodiphenylamine has the molecular formula C12H10N2O and a molecular weight of 198.22 g/mol. Its IUPAC name is 4-nitroso-N-phenylaniline.

What is 4-Nitrosodiphenylamine used for?

4-Nitrosodiphenylamine is supplied as a characterised reference material related to Nitroso. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Nitrosodiphenylamine can I order?

We supply 4-Nitrosodiphenylamine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Nitrosodiphenylamine?

Yes. Every lot of 4-Nitrosodiphenylamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Nitrosodiphenylamine be shipped internationally?

Yes. 4-Nitrosodiphenylamine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.