4-Oxo-9-Cis Retinoic Acid

Name: 4-Oxo-9-Cis Retinoic Acid
Brand: Vaqora Chemicals
SKU: VQ-026243

About 4-Oxo-9-Cis Retinoic Acid

4-Oxo-9-Cis Retinoic Acid is a metabolite or degradation product of Isotretinoin carrying the CAS registry number 150737-18-1. Its molecular formula is C20H26O3 and its molecular weight is 314.4 g/mol. Systematically, it is named (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxocyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid. Common synonyms include 4-oxo Alitretinoin and 9-cis-4-oxoretinoic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Isotretinoin, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4-Oxo-9-Cis Retinoic Acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Isotretinoin

View every impurity, metabolite and intermediate we list for Isotretinoin.

Isotretinoin impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Oxo-9-Cis Retinoic Acid
Catalogue No.	VQ-026243
CAS Number	150737-18-1
IUPAC name	(2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxocyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
Molecular formula	C₂₀H₂₆O₃
Molecular weight	314.4 g/mol
Exact mass	314.1882
Grade	Reference Standard
HSN code	38229090
InChIKey	GGCUJPCCTQNTJF-NAXRMXIQSA-N
SMILES	CC1=C(C(CCC1=O)(C)C)/C=C/C(=C\C=C\C(=C\C(=O)O)\C)/C
PubChem CID	9972939

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	1 / 3
TPSA	54.4 Å²
Synonyms	4-oxo Alitretinoin, 9-cis-4-oxoretinoic acid, 4-keto-9-cis-retinoic acid, (9cis)-4-oxoretinoic acid, 9-cis-4-ketoretinoic acid, 4-Keto 9-cis Retinoic Acid, Retinoic acid, 4-oxo-, 9-cis-

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P203, P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Oxo-9-Cis Retinoic Acid?

The CAS Registry Number of 4-Oxo-9-Cis Retinoic Acid is 150737-18-1. It is also known as 4-oxo Alitretinoin, 9-cis-4-oxoretinoic acid, 4-keto-9-cis-retinoic acid.

What is the molecular formula and molecular weight of 4-Oxo-9-Cis Retinoic Acid?

4-Oxo-9-Cis Retinoic Acid has the molecular formula C20H26O3 and a molecular weight of 314.4 g/mol. Its IUPAC name is (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxocyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid.

What is 4-Oxo-9-Cis Retinoic Acid used for?

4-Oxo-9-Cis Retinoic Acid is supplied as a characterised reference material related to Isotretinoin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Oxo-9-Cis Retinoic Acid can I order?

We supply 4-Oxo-9-Cis Retinoic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Oxo-9-Cis Retinoic Acid?

Yes. Every lot of 4-Oxo-9-Cis Retinoic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Oxo-9-Cis Retinoic Acid be shipped internationally?

Yes. 4-Oxo-9-Cis Retinoic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.