4-Oxo Cyclophosphamide

Name: 4-Oxo Cyclophosphamide
Brand: Vaqora Chemicals
SKU: VQ-047892

About 4-Oxo Cyclophosphamide

Vaqora Chemicals supplies 4-Oxo Cyclophosphamide, a process intermediate or related compound of Cyclophosphamide registered under CAS number 27046-19-1. With the molecular formula C7H13Cl2N2O3P, it has a molar mass of 275.07 g/mol. Systematically, it is named 2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2lambda5-oxazaphosphinan-4-one. Common synonyms include 4-Ketocyclophosphamide and Oxo-Endoxan.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is a process intermediate or related compound in the synthesis of Cyclophosphamide, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 4-Oxo Cyclophosphamide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Cyclophosphamide

View every impurity, metabolite and intermediate we list for Cyclophosphamide.

Cyclophosphamide impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Oxo Cyclophosphamide
Catalogue No.	VQ-047892
CAS Number	27046-19-1
IUPAC name	2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2lambda5-oxazaphosphinan-4-one
Molecular formula	C₇H₁₃Cl₂N₂O₃P
Molecular weight	275.07 g/mol
Exact mass	274.0041
HSN code	2933
InChIKey	VBMZHOCORXMDJU-UHFFFAOYSA-N
SMILES	C1COP(=O)(NC1=O)N(CCCl)CCCl
PubChem CID	33676

Physical properties
Physical form	Solid
LogP (XLogP3)	0.1
H-bond donors / acceptors	1 / 4
TPSA	58.6 Å²
Synonyms	4-Ketocyclophosphamide, 2-(Bis(2-chloroethyl)amino)tetrahydro-4H-1,3,2-oxazaphosphorin-4-one 2-oxide, 2-(bis(2-chloroethyl)amino)-2-oxo-1,3,2$l^(5)-oxazaphosphinan-4-one, 2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2$l^{5}-oxazaphosphinan-4-one, Oxo-Endoxan, Asta 5160, 4H-1,3,2-Oxazaphosphorin-4-one, 2-(bis(2-chloroethyl)amino)tetrahydro-, 2-oxide, 4H-1,3,2-Oxazophosphorin-4-one, 2-(bis(2-chloroethyl)amino)tetrahydro-, 2-oxide, 2-(Bis(2-chloroethyl)amino)-1,3,2-oxazaphosphinan-4-one 2-oxide, 2-[Bis(2-chloroethyl)amino]-1,3,2-oxazaphosphinan-4-one 2-oxide #

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Oxo Cyclophosphamide?

The CAS Registry Number of 4-Oxo Cyclophosphamide is 27046-19-1. It is also known as 4-Ketocyclophosphamide, 2-(Bis(2-chloroethyl)amino)tetrahydro-4H-1,3,2-oxazaphosphorin-4-one 2-oxide, 2-(bis(2-chloroethyl)amino)-2-oxo-1,3,2$l^(5)-oxazaphosphinan-4-one.

What is the molecular formula and molecular weight of 4-Oxo Cyclophosphamide?

4-Oxo Cyclophosphamide has the molecular formula C7H13Cl2N2O3P and a molecular weight of 275.07 g/mol. Its IUPAC name is 2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2lambda5-oxazaphosphinan-4-one.

What is 4-Oxo Cyclophosphamide used for?

4-Oxo Cyclophosphamide is supplied as a characterised reference material related to Cyclophosphamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Oxo Cyclophosphamide can I order?

We supply 4-Oxo Cyclophosphamide, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Oxo Cyclophosphamide?

Yes. Every lot of 4-Oxo Cyclophosphamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Oxo Cyclophosphamide be shipped internationally?

Yes. We export 4-Oxo Cyclophosphamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.