4-(Tert-Butyl)-N-(5-hydroxy-6-(2-(2-hydroxyet… 1257099-41-4

Name: 4-(Tert-Butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide
Brand: Vaqora Chemicals
SKU: VQ-036008

About 4-(Tert-Butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide

4-(Tert-Butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide (CAS 1257099-41-4) is a metabolite or degradation product of Bosentan offered by Vaqora Chemicals. The compound has the formula C22H27N5O6S, corresponding to a molecular weight of 489.5 g/mol. The IUPAC name is 4-tert-butyl-N-[5-hydroxy-6-[2-(2-hydroxyethoxy)ethoxy]-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Bosentan, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 4-(Tert-Butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Bosentan

View every impurity, metabolite and intermediate we list for Bosentan.

Bosentan impurities

Specifications & identifiers

Chemical identifiers
Product name	4-(Tert-Butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide
Catalogue No.	VQ-036008
CAS Number	1257099-41-4
IUPAC name	4-tert-butyl-N-[5-hydroxy-6-[2-(2-hydroxyethoxy)ethoxy]-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
Molecular formula	C₂₂H₂₇N₅O₆S
Molecular weight	489.5 g/mol
Exact mass	489.1682
Grade	Reference Standard
HSN code	38229090
InChIKey	QGDQUZAUKUCPQO-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCOCCO)O
PubChem CID	135927705

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	3 / 11
TPSA	165 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-(Tert-Butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide?

The CAS Registry Number of 4-(Tert-Butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide is 1257099-41-4.

What is the molecular formula and molecular weight of 4-(Tert-Butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide?

4-(Tert-Butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide has the molecular formula C22H27N5O6S and a molecular weight of 489.5 g/mol. Its IUPAC name is 4-tert-butyl-N-[5-hydroxy-6-[2-(2-hydroxyethoxy)ethoxy]-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide.

What is 4-(Tert-Butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide used for?

4-(Tert-Butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide is supplied as a characterised reference material related to Bosentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-(Tert-Butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide can I order?

We supply 4-(Tert-Butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-(Tert-Butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide?

Yes. Every lot of 4-(Tert-Butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-(Tert-Butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide be shipped internationally?

Yes. We export 4-(Tert-Butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.